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自发性冠状动脉夹层致甲状腺危象患者发生心源性猝死的风险

Risk of sudden cardiac death in a case of spontaneous coronary artery dissection presenting with thyroid storm.

机构信息

Division of Cardiology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2022 May;26(10):3712-3717. doi: 10.26355/eurrev_202205_28867.

Abstract

OBJECTIVE

Spontaneous coronary artery dissection (SCAD) is a spontaneous separation of the coronary artery wall whose etiology appears to be poorly understood. SCAD is a rare cause of acute coronary syndromes, and it is a life-threatening condition.

CASE REPORT

We report the case of a young woman who developed SCAD during a thyroid storm (TS).

RESULTS

To the best of our knowledge, this is the first reported case of SCAD during a TS, and it suggests a possible association between high levels of circulating thyroid hormones and SCAD susceptibility.

CONCLUSIONS

Early identification of SCAD predisposing factors is important to identify high-risk patients. In patients presenting to the emergency department because of chest pain with a history of dysthyroidism, early determination of thyroid hormones and troponin could prevent certain forms of sudden cardiac death.

摘要

目的

自发性冠状动脉夹层(SCAD)是冠状动脉壁的自发性分离,其病因似乎尚不清楚。SCAD 是急性冠状动脉综合征的罕见原因,是一种危及生命的疾病。

病例报告

我们报告了一例在甲状腺危象(TS)期间发生 SCAD 的年轻女性病例。

结果

据我们所知,这是首例 TS 期间发生的 SCAD 病例,提示循环甲状腺激素水平升高与 SCAD 易感性之间可能存在关联。

结论

早期识别 SCAD 的易患因素对于确定高危患者很重要。对于因甲状腺功能异常病史而胸痛就诊于急诊科的患者,早期测定甲状腺激素和肌钙蛋白可预防某些形式的心脏性猝死。

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