Department of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.
Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Aniridia Research, Saarland University, Homburg/Saar, Germany.
Acta Ophthalmol. 2022 Dec;100(8):e1675-e1684. doi: 10.1111/aos.15190. Epub 2022 Jun 1.
Ocular magnification and aniseikonia after cataract surgery has been widely ignored in modern cataract surgery. The purpose of this study was to analyse ocular magnification and inter-individual differences in a normal cataract population with a focus on monovision.
From a large dataset containing biometric measurements (IOLMaster 700) of both eyes of 9734 patients prior to cataract surgery, eyes were indexed randomly as primary (P) and secondary (S). Intraocular lens power (IOLP) was derived for the HofferQ, Haigis and Castrop formulae for emmetropia for P and emmetropia or myopia (-0.5 to -2 dpt) for S to simulate monovision. Based on the pseudophakic eye model in addition to these formulae, ocular magnification was extracted using matrix algebra (refraction and translation matrices and a system matrix describing the optical property of the entire spectacle corrected or uncorrected eye).
With emmetropia for P and S the IOLP differences (S-P) showed a standard deviation of 0.162/0.156/0.157 dpt and ocular magnification differences yielded a standard deviation of 0.0414/0.0405/0.0408 mm/mrad for the HofferQ/Haigis/Castrop setting. Simulating monovision, the myopic eye (S) showed a systematically smaller mean absolute spectacle corrected ocular magnification than the emmetropic eye (-0.0351/-0.0340/-0.0336, respectively, relative magnification around 2%). If myopia in the S eye remains uncorrected, the reduction of ocular magnification is much smaller (around 0.2-0.3%).
Vergence formulae for IOLP calculation sometimes implicitly define a pseudophakic eye model which can be directly used to predict ocular magnification after cataract surgery. Despite a strong similarity of both eyes, ocular magnification does not fully match between eyes and the prediction of ocular magnification and aniseikonia might be relevant to avoid eikonic problems in the pseudophakic eye.
在现代白内障手术中,术后的眼球放大和不等像已被广泛忽视。本研究的目的是分析正常白内障人群中的眼球放大和个体间差异,重点关注单视。
从包含 9734 例患者术前双眼生物测量数据(IOLMaster 700)的大型数据集,将眼随机索引为主要眼(P)和次要眼(S)。对于 P 眼的正视眼和 S 眼的正视眼或近视(-0.5 至-2 DPT),推导了 HofferQ、Haigis 和 Castrop 公式的眼内晶状体屈光力(IOLP),以模拟单视。基于模拟无晶状体眼模型,以及这些公式,使用矩阵代数(屈光和平移矩阵以及描述整个矫正或未矫正眼镜眼光学特性的系统矩阵)提取眼球放大。
对于 P 眼和 S 眼的正视眼,IOLP 差异(S-P)的标准差为 0.162/0.156/0.157 DPT,眼球放大差异的标准差为 0.0414/0.0405/0.0408 毫米/弧度,对于 HofferQ/Haigis/Castrop 设置。模拟单视时,近视眼(S)的平均绝对矫正眼镜眼球放大明显小于正视眼(分别为-0.0351/-0.0340/-0.0336,相对放大率约为 2%)。如果 S 眼的近视仍未矫正,眼球放大的减少要小得多(约 0.2-0.3%)。
IOLP 计算的聚散公式有时会隐含定义一个模拟无晶状体眼模型,该模型可直接用于预测白内障手术后的眼球放大。尽管双眼非常相似,但眼球放大并不完全匹配,眼球放大和不等像的预测可能与避免模拟无晶状体眼中的像差问题有关。