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恶性高热易感个体次极量运动期间的体温调节、血浆儿茶酚胺和代谢产物水平

Thermoregulation, plasma catecholamine and metabolite levels during submaximal work in individuals susceptible to malignant hyperpyrexia.

作者信息

Green J H, Ellis F R, Halsall P J, Campbell I T, Currie S, Caddy J

出版信息

Acta Anaesthesiol Scand. 1987 Feb;31(2):122-6. doi: 10.1111/j.1399-6576.1987.tb02533.x.

DOI:10.1111/j.1399-6576.1987.tb02533.x
PMID:3564867
Abstract

Measurements of body temperature, respiratory gas exchange, sweat evaporation rate and circulating levels of catecholamines, lactate, pyruvate, free fatty acids and glucose were made in seven patients susceptible to malignant hyperpyrexia (MHS) and in seven control subjects during 2 h of treadmill walking at 40% of maximum oxygen consumption. These studies took place in an ambient temperature of 22 degrees C. The MHS patients displayed the same thermoregulatory, plasma catecholamine and metabolic responses as the control subjects. The results of the present study suggest that non-competitive, low-intensity, steady-state exercise need not be contraindicated for MHS patients.

摘要

在七名易患恶性高热(MHS)的患者和七名对照受试者中,于22摄氏度的环境温度下,以最大耗氧量的40%进行2小时跑步机行走期间,测量了体温、呼吸气体交换、汗液蒸发率以及儿茶酚胺、乳酸、丙酮酸、游离脂肪酸和葡萄糖的循环水平。MHS患者表现出与对照受试者相同的体温调节、血浆儿茶酚胺和代谢反应。本研究结果表明,非竞争性、低强度、稳态运动对MHS患者不一定是禁忌的。

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