Sundberg A, Wattwil M, Wiklund L
Acta Anaesthesiol Scand. 1987 Feb;31(2):139-42. doi: 10.1111/j.1399-6576.1987.tb02536.x.
In ten elderly patients subjected to extensive thoracolumbar epidural anaesthesia, circulatory changes were studied before and during sympathetic stimulation. Induced hypercapnia was used as a sympathetic stimulus. After establishment of the epidural anaesthesia, which extended from T1 to L2, there were decreases in heart rate, mean arterial blood pressure, cardiac output and systemic vascular resistance. Hypercapnia before the epidural block increased heart rate, arterial blood pressure and cardiac output, while hypercapnia after established epidural block induced only a slight increase in arterial blood pressure. The results indicate that in spite of an extensive epidural block, there are some "escaped" sympathetic nerve fibres that can be mobilized during sympathetic stimulation.
在10例接受广泛胸腰段硬膜外麻醉的老年患者中，研究了交感神经刺激前后的循环变化。采用诱导性高碳酸血症作为交感神经刺激。在建立从T1至L2的硬膜外麻醉后，心率、平均动脉血压、心输出量和全身血管阻力均下降。硬膜外阻滞前的高碳酸血症会增加心率、动脉血压和心输出量，而硬膜外阻滞建立后的高碳酸血症仅引起动脉血压略有升高。结果表明，尽管进行了广泛的硬膜外阻滞，但仍有一些“逃逸”的交感神经纤维在交感神经刺激期间可被调动起来。
