Division of Cardiovascular Surgery.
Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Curr Opin Organ Transplant. 2022 Jun 1;27(3):191-197. doi: 10.1097/MOT.0000000000000978.
Lung transplant (LTx) evaluation and selection of candidates with connective tissue disease (CTD) remains controversial and varies between centers, and the optimal candidate selection is still controversial.
Recent United States and European publications have reported reasonable short-term and long-term LTx outcomes in patients with CTD to other lung fibrosis patients without CTD. This article discusses the recently published International Society for Heart and Lung Transplantation (ISHLT) consensus document recommendations to evaluate and select CTD candidates, the importance of early referral, posttransplant management, and the involvement of a multidisciplinary team.
Future standardized practices among centers adapting the 2021 ISHLT consensus recommendations to evaluate and select CTD candidates will allow risk stratification, determine the best candidates, and facilitate the most successful long-term LTx outcomes.
肺移植（LTx）评估和结缔组织疾病（CTD）患者的选择在不同中心之间仍然存在争议，并且最佳患者选择仍存在争议。
最近美国和欧洲的出版物报告了 CTD 患者与非 CTD 其他肺纤维化患者的合理短期和长期 LTx 结果。本文讨论了最近发表的国际心肺移植学会（ISHLT）共识文件建议，以评估和选择 CTD 患者，早期转介的重要性，移植后的管理以及多学科团队的参与。
未来中心之间的标准化实践，适应 2021 年 ISHLT 共识建议以评估和选择 CTD 患者，将允许风险分层，确定最佳患者，并促进最成功的长期 LTx 结果。
