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小鼠前庭神经节的髓鞘形成。

Myelination of the mouse vestibular ganglion.

作者信息

Dechesne C J, Desmadryl G, Dememes D

出版信息

Acta Otolaryngol. 1987 Jan-Feb;103(1-2):18-23. doi: 10.3109/00016488709134693.

DOI:10.3109/00016488709134693
PMID:3564926
Abstract

Myelination of mouse vestibular ganglion cells and preganglionic fibres was examined by light and electron microscopy from gestation day 16 to postnatal day 23. Myelination of the preganglionic fibres occurred essentially during the first 2 days after birth and was almost complete by postnatal day 7. Myelination of the ganglion cells occurred later and lasted longer than that of the fibres. Its onset was observed on postnatal day 9 and the myelin sheaths had fully developed structures 2 weeks later. Thus, myelination of vestibular ganglion neurons appeared to be the latest event to take place in the maturation of the peripheral vestibular system. The sequences of myelination are discussed with respect to those of electrophysiological maturation.

摘要

从妊娠第16天至出生后第23天,通过光学显微镜和电子显微镜检查了小鼠前庭神经节细胞和节前纤维的髓鞘形成。节前纤维的髓鞘形成主要发生在出生后的头2天内,到出生后第7天几乎完成。神经节细胞的髓鞘形成较晚,持续时间比纤维的髓鞘形成更长。其起始于出生后第9天被观察到,2周后髓鞘具有完全发育的结构。因此,前庭神经节神经元的髓鞘形成似乎是外周前庭系统成熟过程中发生的最晚事件。结合电生理成熟的顺序对髓鞘形成的顺序进行了讨论。

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