Dememes D, Dechesne C, Legrand C, Sans A
Brain Res. 1986 Feb;390(1):147-52. doi: 10.1016/0165-3806(86)90163-x.
The morphogenetic effects of congenital hypothyroidism on the development of rat vestibular receptor cells and ganglia were investigated by transmission electron microscopy. Vestibular ganglia are especially immature and characterized by an absence of a myelin sheath around the perikarya. The type I hair cells have a delayed development in their innervation. The last cells to differentiate and the last synaptic contacts to develop are the most affected. The most remarkable result of hypothyroidism is the persistent immaturity of the synaptic contacts.
通过透射电子显微镜研究先天性甲状腺功能减退对大鼠前庭感受器细胞和神经节发育的形态发生学影响。前庭神经节特别不成熟，其特征是神经元胞体周围缺乏髓鞘。I型毛细胞的神经支配发育延迟。最后分化的细胞和最后形成的突触联系受影响最大。甲状腺功能减退最显著的结果是突触联系持续不成熟。
