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急性心肌炎伴严重发热和血小板减少综合征

Acute Myocarditis with Severe Fever and Thrombocytopenia Syndrome.

作者信息

Okutsu Shota, Futami Makito, Arimura Tadaaki, Ohki Kosuke, Hiyoshi Tetsuya, Sakihara Eishi, Kato Yoshifumi, Ueda Yoko, Yano Masaya, Takeshita Morishige, Ishikura Hiroyasu, Suzuki Tadaki, Kato Seiya, Miura Shin-Ichiro, Nabeshima Shigeki

机构信息

General Medicine, Fukuoka University Hospital, Japan.

Department of Cardiology, Fukuoka University Faculty of Medicine, Japan.

出版信息

Intern Med. 2022;61(11):1779-1784. doi: 10.2169/internalmedicine.7018-21. Epub 2022 Jun 1.

DOI:10.2169/internalmedicine.7018-21
PMID:35650116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9259318/
Abstract

A 67-year-old man, hospitalized with fever and pancytopenia, experienced cardiogenic shock on the 3rd day of hospitalization. He complained of chest pain and exhibited cardiac dysfunction, upregulated serum troponin levels, and an ST elevation on electrocardiogram. Severe fever with thrombocytopenia syndrome (SFTS) was suspected based on the symptom course after a tick bite and was definitively diagnosed using the serum polymerase chain reaction (PCR) test. An endomyocardial biopsy performed in the convalescent phase revealed a sign of myocardial inflammation with increases in CD3- and CD68-positive cells. We herein report the first case of acute myocarditis complicated with SFTS.

摘要

一名67岁男性因发热和全血细胞减少入院,住院第3天发生心源性休克。他主诉胸痛,出现心脏功能障碍、血清肌钙蛋白水平升高及心电图ST段抬高。根据蜱叮咬后的症状过程怀疑为重症发热伴血小板减少综合征(SFTS),并通过血清聚合酶链反应(PCR)检测确诊。恢复期进行的心内膜心肌活检显示心肌炎症迹象,CD3和CD68阳性细胞增加。我们在此报告首例合并SFTS的急性心肌炎病例。

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本文引用的文献

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BMC Infect Dis. 2024 Feb 22;24(1):240. doi: 10.1186/s12879-024-09096-4.
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Cardiac Abnormalities in Patients With Severe Fever With Thrombocytopenia Syndrome: A Systematic Review.严重发热伴血小板减少综合征患者的心脏异常:一项系统评价
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BMC Infect Dis. 2019 Mar 18;19(1):266. doi: 10.1186/s12879-019-3904-8.
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Hemophagocytic Lymphohistiocytosis in a Fatal Case of Severe Fever with Thrombocytopenia Syndrome.重症发热伴血小板减少综合征致死病例中的噬血细胞性淋巴组织细胞增生症
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