通过氧化还原门控的构象限制来控制SpyTag/SpyCatcher反应活性。
Controlling SpyTag/SpyCatcher Reactivity via Redox-Gated Conformational Restriction.
作者信息
Wu Wen-Hao, Wei Jingjing, Zhang Wen-Bin
机构信息
Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
College of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, Henan 455000, P. R. China.
出版信息
ACS Macro Lett. 2018 Nov 20;7(11):1388-1393. doi: 10.1021/acsmacrolett.8b00668. Epub 2018 Nov 12.
Herein, we report that the reactivity of genetically encoded SpyTag/SpyCatcher chemistry can be manipulated via redox-gated conformational restriction, which facilitates the preparation of all-protein-based hydrogel with latent reactive sites for subsequent covalent functionalization.
在此，我们报道了基因编码的SpyTag/SpyCatcher化学的反应性可以通过氧化还原门控的构象限制来操纵，这有助于制备具有潜在反应位点的全蛋白基水凝胶，用于后续的共价功能化。
Zotero 插件