Melugin Heath P, Hale Rena F, Lee Dustin R, LaPrade Matthew D, Okoroha Kelechi R, Sierra Rafael J, Trousdale Robert T, Levy Bruce A, Krych Aaron J
Department of Sports Medicine Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
J Hip Preserv Surg. 2022 Jan 19;9(1):18-21. doi: 10.1093/jhps/hnac007. eCollection 2022 Jan.
Hip dysplasia is a common cause of hip pain and a known risk factor for hip osteoarthritis (OA) and early total hip arthroplasty (THA). Unfortunately, little is known about the specific factors associated with an increased risk of OA. The purpose was (i) to report the overall rate of symptomatic hip OA and THA and (ii) to identify radiographic features and patient characteristics associated with the development of symptomatic hip OA. A geographic database was used to identify all patients aged 14-50 years old diagnosed with symptomatic hip dysplasia between 2000 and 2016. Kaplan-Meier analysis was used to determine the rate of symptomatic hip OA, defined as a Tönnis grade of ≥1 on hip radiograph. Univariate and multivariate proportional hazard regression models were performed to determine risk factors for OA. One hundred and fifty-nine hips (144 patients) with hip dysplasia (52 F:107 M) out of 1893 patients with hip pain were included. Of these, 45 (28%) had severe hip dysplasia with a lateral center-edge angle ≤18°. Mean age at time of presentation was 26.1 (±10.1) years. Mean follow-up time was 8.2 (±5) years. The rate of OA was 20%. THA was performed in 11% of patients. Body mass index >29 ( = 0.03) and increased age ( < 0.01) were risk factors for OA. Patients with symptomatic hip dysplasia are at significant risk of developing hip OA. Body mass index >29 and age ≥35 years at the time of presentation with hip pain were risk factors for hip OA.
髋关节发育不良是髋关节疼痛的常见原因，也是髋骨关节炎（OA）和早期全髋关节置换术（THA）的已知危险因素。遗憾的是，对于与OA风险增加相关的具体因素知之甚少。目的是（i）报告有症状的髋OA和THA的总体发生率，以及（ii）确定与有症状的髋OA发生相关的影像学特征和患者特征。利用一个地理数据库识别出2000年至2016年间诊断为有症状的髋关节发育不良的所有14至50岁患者。采用Kaplan-Meier分析来确定有症状的髋OA的发生率，定义为髋关节X线片上Tönnis分级≥1级。进行单因素和多因素比例风险回归模型以确定OA的危险因素。纳入了1893例髋部疼痛患者中的159例髋关节发育不良患者（144例患者）（52例女性：107例男性）。其中，45例（28%）有严重的髋关节发育不良，外侧中心边缘角≤18°。就诊时的平均年龄为26.1（±10.1）岁。平均随访时间为8.2（±5）年。OA的发生率为20%。11%的患者接受了THA。体重指数>29（=0.03）和年龄增加（<0.01）是OA的危险因素。有症状的髋关节发育不良患者发生髋OA的风险显著。就诊时体重指数>29且年龄≥35岁是髋OA的危险因素。
