Suppr超能文献

60 岁以上患者行开放式楔形胫骨高位截骨术与全膝关节置换术的短期 KOOS 评分相似:一项倾向评分匹配队列研究。

Similar short-term KOOS between open-wedge high tibial osteotomy and total knee arthroplasty in patients over age 60: A propensity score-matched cohort study.

机构信息

Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.

Akiyama Clinic, Fukuoka, Japan.

出版信息

Mod Rheumatol. 2023 Apr 13;33(3):623-628. doi: 10.1093/mr/roac052.

Abstract

OBJECTIVES

The purpose of the present study was to evaluate improvement in the Knee Injury and Osteoarthritis Outcome Score (KOOS) after open-wedge high tibial osteotomy (HTO) in comparison with total knee arthroplasty (TKA) in cohorts over age 60 matched by pre-operative age, gender, body mass index (BMI), hip-knee-ankle angle (HKAA), KOOS sub-scores, and osteoarthritis (OA) grade.

METHODS

Propensity score matching was performed between 162 HTO patients and 134 TKA patients. When calculating the propensity score by multivariate logistic regression analysis, the following pre-operative confounders were included: age, gender, BMI, HKAA, KOOS sub-scores, and OA grade. Consequently, a total of 55 patients were included in each group. The Student's t-test was used to analyse differences in the post-operative KOOS sub-scores between groups.

RESULTS

After propensity score matching, all matched pre-operative valuables were identical, with no significant differences between the HTO and TKA groups. None of the post-operative KOOS sub-scores at 1 year after surgery showed a significant difference between the HTO and TKA groups. Both groups demonstrated significant and comparable post-operative improvement in every KOOS sub-score.

CONCLUSIONS

In patients over age 60, there was no significant difference in short-term pain relief and improvements in activity and quality of life between HTO and TKA after propensity score matching including pre-operative age, KOOS sub-scores, and OA grade. HTO is a joint preservation procedure that is valid for knee OA even in individuals over age 60.

摘要

目的

本研究旨在评估与全膝关节置换术(TKA)相比,在年龄超过 60 岁且匹配术前年龄、性别、体重指数(BMI)、髋膝踝角(HKAA)、KOOS 亚量表和骨关节炎(OA)分级的患者中,行开放式楔形胫骨高位截骨术(HTO)后 KOOS 评分的改善情况。

方法

通过倾向性评分匹配比较了 162 例 HTO 患者和 134 例 TKA 患者。在进行多变量逻辑回归分析计算倾向性评分时,纳入了以下术前混杂因素:年龄、性别、BMI、HKAA、KOOS 亚量表和 OA 分级。因此,每组纳入了 55 例患者。采用 Student's t 检验分析两组间术后 KOOS 亚量表的差异。

结果

经倾向性评分匹配后,所有匹配的术前值均相同,HTO 和 TKA 组之间无显著差异。术后 1 年,没有任何 KOOS 亚量表的评分在 HTO 和 TKA 组之间存在显著差异。两组在每个 KOOS 亚量表的术后改善均显著且相似。

结论

在年龄超过 60 岁的患者中,在包括术前年龄、KOOS 亚量表和 OA 分级在内的倾向性评分匹配后,HTO 和 TKA 治疗膝 OA 的短期缓解疼痛以及改善活动和生活质量方面没有显著差异。HTO 是一种保膝手术,即使在 60 岁以上的患者中,对于膝 OA 也是有效的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验