Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.
Akiyama Clinic, Fukuoka, Japan.
Mod Rheumatol. 2023 Apr 13;33(3):623-628. doi: 10.1093/mr/roac052.
The purpose of the present study was to evaluate improvement in the Knee Injury and Osteoarthritis Outcome Score (KOOS) after open-wedge high tibial osteotomy (HTO) in comparison with total knee arthroplasty (TKA) in cohorts over age 60 matched by pre-operative age, gender, body mass index (BMI), hip-knee-ankle angle (HKAA), KOOS sub-scores, and osteoarthritis (OA) grade.
Propensity score matching was performed between 162 HTO patients and 134 TKA patients. When calculating the propensity score by multivariate logistic regression analysis, the following pre-operative confounders were included: age, gender, BMI, HKAA, KOOS sub-scores, and OA grade. Consequently, a total of 55 patients were included in each group. The Student's t-test was used to analyse differences in the post-operative KOOS sub-scores between groups.
After propensity score matching, all matched pre-operative valuables were identical, with no significant differences between the HTO and TKA groups. None of the post-operative KOOS sub-scores at 1 year after surgery showed a significant difference between the HTO and TKA groups. Both groups demonstrated significant and comparable post-operative improvement in every KOOS sub-score.
In patients over age 60, there was no significant difference in short-term pain relief and improvements in activity and quality of life between HTO and TKA after propensity score matching including pre-operative age, KOOS sub-scores, and OA grade. HTO is a joint preservation procedure that is valid for knee OA even in individuals over age 60.
本研究旨在评估与全膝关节置换术(TKA)相比,在年龄超过 60 岁且匹配术前年龄、性别、体重指数(BMI)、髋膝踝角(HKAA)、KOOS 亚量表和骨关节炎(OA)分级的患者中,行开放式楔形胫骨高位截骨术(HTO)后 KOOS 评分的改善情况。
通过倾向性评分匹配比较了 162 例 HTO 患者和 134 例 TKA 患者。在进行多变量逻辑回归分析计算倾向性评分时,纳入了以下术前混杂因素:年龄、性别、BMI、HKAA、KOOS 亚量表和 OA 分级。因此,每组纳入了 55 例患者。采用 Student's t 检验分析两组间术后 KOOS 亚量表的差异。
经倾向性评分匹配后,所有匹配的术前值均相同,HTO 和 TKA 组之间无显著差异。术后 1 年,没有任何 KOOS 亚量表的评分在 HTO 和 TKA 组之间存在显著差异。两组在每个 KOOS 亚量表的术后改善均显著且相似。
在年龄超过 60 岁的患者中,在包括术前年龄、KOOS 亚量表和 OA 分级在内的倾向性评分匹配后,HTO 和 TKA 治疗膝 OA 的短期缓解疼痛以及改善活动和生活质量方面没有显著差异。HTO 是一种保膝手术,即使在 60 岁以上的患者中,对于膝 OA 也是有效的。