情绪脑回路成熟的原则。
Principles of emotional brain circuit maturation.
机构信息
Departments of Pediatrics, Anatomy and Neurobiology, and Neurology, University of California-Irvine, Irvine, CA, USA.
出版信息
Science. 2022 Jun 3;376(6597):1055-1056. doi: 10.1126/science.abn4016. Epub 2022 Jun 2.
Abstract
Early-life environmental signals contribute to how the brain handles reward, stress, and fear.
摘要
早期生活环境信号有助于大脑处理奖励、压力和恐惧。
相似文献
1
Principles of emotional brain circuit maturation.情绪脑回路成熟的原则。
Science. 2022 Jun 3;376(6597):1055-1056. doi: 10.1126/science.abn4016. Epub 2022 Jun 2.
2
Emotional memory: in search of systems and synapses.情绪记忆：探寻相关系统与突触
Ann N Y Acad Sci. 1993 Nov 17;702:149-57. doi: 10.1111/j.1749-6632.1993.tb17246.x.
3
The possible significance for learning of some different types of synaptic modification.某些不同类型突触修饰对学习的潜在意义。
Biochem Soc Trans. 1978;6(5):841-4. doi: 10.1042/bst0060841.
4
Neural plasticity and emotional memory.神经可塑性与情绪记忆。
Dev Psychopathol. 1998 Fall;10(4):829-55. doi: 10.1017/s0954579498001898.
5
The Impact of Parent-Infant Interaction on Epigenetic Plasticity Mediating Synaptic Adaptations in the Infant Brain.亲子互动对介导婴儿大脑突触适应性的表观遗传可塑性的影响。
Psychopathology. 2016;49(4):201-210. doi: 10.1159/000448055. Epub 2016 Sep 27.
6
'Negativity bias' in risk for depression and anxiety: brain-body fear circuitry correlates, 5-HTT-LPR and early life stress.抑郁和焦虑风险中的“消极偏向”：脑-体恐惧神经回路相关性、5-羟色胺转运体基因启动子区域多态性（5-HTT-LPR）与早期生活应激
Neuroimage. 2009 Sep;47(3):804-14. doi: 10.1016/j.neuroimage.2009.05.009. Epub 2009 May 14.
7
Tuning hippocampal synapses by stress-hormones: Relevance for emotional memory formation.应激激素对海马体突触的调节：与情绪记忆形成的相关性。
Brain Res. 2015 Sep 24;1621:114-20. doi: 10.1016/j.brainres.2015.04.010. Epub 2015 Apr 20.
8
The influence of unpredictable, fragmented parental signals on the developing brain.不可预测的、碎片化的父母信号对发育中大脑的影响。
Front Neuroendocrinol. 2019 Apr;53:100736. doi: 10.1016/j.yfrne.2019.01.002. Epub 2019 Jan 31.
9
microRNA and mRNA profiles in the amygdala are relevant to fear memory induced by physical or psychological stress.杏仁核中的 microRNA 和 mRNA 谱与物理或心理应激引起的恐惧记忆有关。
J Neurophysiol. 2019 Sep 1;122(3):1002-1022. doi: 10.1152/jn.00215.2019. Epub 2019 Jul 3.
10
Long-term potentiation as a candidate mnemonic device.作为一种候选记忆机制的长时程增强效应。
Brain Res. 1984 Mar;319(1):15-28. doi: 10.1016/0165-0173(84)90027-4.
引用本文的文献
1
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities.产前应激会在不同的γ-氨基丁酸能神经元群体中诱发短暂的发育改变，并导致长期的行为异常。
Neurobiol Stress. 2025 Aug 6;38:100749. doi: 10.1016/j.ynstr.2025.100749. eCollection 2025 Sep.
2
Attachment as Prediction: Insights from Cognitive and Developmental Neuroscience.作为预测的依恋：来自认知与发展神经科学的见解
Curr Dir Psychol Sci. 2025 Jun;34(3):195-206. doi: 10.1177/09637214251313714. Epub 2025 Feb 20.
3
Genetic risk-dependent brain markers of resilience to childhood Trauma.童年创伤复原力的基因风险依赖性脑标志物
Nat Commun. 2025 Jul 5;16(1):6219. doi: 10.1038/s41467-025-61471-0.
4
Brain White Matter Alterations in Young Adults with Childhood Emotional Neglect Experience.童年期遭受情感忽视的年轻成年人的脑白质改变
Behav Sci (Basel). 2025 May 28;15(6):746. doi: 10.3390/bs15060746.
5
In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super-Resolution Imaging and Genome Modification.生物分子在体内向神经元的胞质递送用于超分辨率成像和基因组修饰
Adv Sci (Weinh). 2025 Jul;12(25):e2501033. doi: 10.1002/advs.202501033. Epub 2025 Apr 26.
6
A sensitive period for the development of episodic-like memory in mice.小鼠中情景样记忆发展的敏感期。
Curr Biol. 2025 May 5;35(9):2032-2048.e3. doi: 10.1016/j.cub.2025.03.032. Epub 2025 Apr 10.
7
Early-life stress sensitizes response to future stress: Evidence and mechanisms.早期生活应激使机体对未来应激的反应敏感化：证据与机制。
Neurobiol Stress. 2025 Mar 8;35:100716. doi: 10.1016/j.ynstr.2025.100716. eCollection 2025 Mar.
8
The evolving neurobiology of early-life stress.早期生活压力不断演变的神经生物学
Neuron. 2025 May 21;113(10):1474-1490. doi: 10.1016/j.neuron.2025.02.016. Epub 2025 Mar 17.
9
Sensory input, sex and function shape hypothalamic cell type development.感觉输入、性别和功能塑造下丘脑细胞类型的发育。
Nature. 2025 Mar 5. doi: 10.1038/s41586-025-08603-0.
10
Contribution of an under-recognized adversity to child health risk: large-scale, population-based ACEs screening.一种未被充分认识的逆境对儿童健康风险的影响：基于大规模人群的不良童年经历筛查
medRxiv. 2025 Feb 5:2025.02.04.25321682. doi: 10.1101/2025.02.04.25321682.
本文引用的文献
1
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses.早期应激诱导的不成熟 CRH 表达神经元上兴奋性突触的小胶质细胞修剪受损，引发异常的成年应激反应。
Cell Rep. 2022 Mar 29;38(13):110600. doi: 10.1016/j.celrep.2022.110600.
2
Vision-dependent specification of cell types and function in the developing cortex.发育皮层中细胞类型和功能的视觉依赖性特化。
Cell. 2022 Jan 20;185(2):311-327.e24. doi: 10.1016/j.cell.2021.12.022.
3
Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS.调控哺乳动物中枢神经系统发育过程中活性依赖型突触修剪的机制。
Nat Rev Neurosci. 2021 Nov;22(11):657-673. doi: 10.1038/s41583-021-00507-y. Epub 2021 Sep 20.
4
Deep brain optogenetics without intracranial surgery.无需颅内手术的深部脑光遗传学。
Nat Biotechnol. 2021 Feb;39(2):161-164. doi: 10.1038/s41587-020-0679-9. Epub 2020 Oct 5.
5
Disruption of hippocampal rhythms via optogenetic stimulation during the critical period for memory development impairs spatial cognition.在记忆发展的关键期通过光遗传刺激破坏海马体节律会损害空间认知能力。
Brain Stimul. 2020 Nov-Dec;13(6):1535-1547. doi: 10.1016/j.brs.2020.08.011. Epub 2020 Aug 29.
6
Neurodevelopmental Optimization after Early-Life Adversity: Cross-Species Studies to Elucidate Sensitive Periods and Brain Mechanisms to Inform Early Intervention.早期逆境后的神经发育优化：阐明敏感时期和大脑机制的跨物种研究，以为早期干预提供信息。
Trends Neurosci. 2020 Oct;43(10):744-751. doi: 10.1016/j.tins.2020.08.001. Epub 2020 Aug 27.
7
Across continents and demographics, unpredictable maternal signals are associated with children's cognitive function.跨越各大洲和人口统计数据，不可预测的母体信号与儿童的认知功能有关。
EBioMedicine. 2019 Aug;46:256-263. doi: 10.1016/j.ebiom.2019.07.025. Epub 2019 Jul 27.
8
Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice.早期生活应激通过影响眶额皮质中的 PV 中间神经元导致雄性小鼠的反转学习出现性别选择性损伤。
Cell Rep. 2018 Nov 27;25(9):2299-2307.e4. doi: 10.1016/j.celrep.2018.11.010.
9
Inhibitory circuit gating of auditory critical-period plasticity.听觉关键期可塑性的抑制性回路门控。
Nat Neurosci. 2018 Feb;21(2):218-227. doi: 10.1038/s41593-017-0064-2. Epub 2018 Jan 22.
10
Stellate cells drive maturation of the entorhinal-hippocampal circuit.星状细胞驱动内侧隔核-海马回路的成熟。
Science. 2017 Mar 17;355(6330). doi: 10.1126/science.aai8178. Epub 2017 Feb 2.
Zotero 插件