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免疫记忆对 SARS-CoV-2 奥密克戎 BA.1 突破感染的作用:是否需要改变疫苗?

Immune memory to SARS-CoV-2 Omicron BA.1 breakthrough infections: To change the vaccine or not?

机构信息

Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, VIC, Australia.

Department of Allergy, Immunology, and Respiratory Medicine, Central Clinical School, Monash University and Alfred Hospital, Melbourne, VIC, Australia. Email:

出版信息

Sci Immunol. 2022 Aug 26;7(74):eabq5901. doi: 10.1126/sciimmunol.abq5901.

Abstract

Analysis of memory B cell responses to Spike antigen after Omicron BA.1 breakthrough infections suggests that "original antigenic sin" is in play.

摘要

分析奥密克戎 BA.1 突破感染后针对刺突抗原的记忆 B 细胞反应表明,“原始抗原性错误”正在发挥作用。

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