Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Neuron. 2022 Jun 1;110(11):1745-1746. doi: 10.1016/j.neuron.2022.04.028.
The trigeminal ganglia (TG) play a crucial role in migraine pathophysiology. In this issue of Neuron, Yang et al. developed a single-cell atlas profiling the transcriptome and epigenome of mouse and human TG, thus providing a roadmap for therapeutic targeting.
三叉神经节 (TG) 在偏头痛发病机制中起着至关重要的作用。在本期《神经元》杂志上,Yang 等人开发了一个单细胞图谱,对小鼠和人类 TG 的转录组和表观基因组进行了分析,为治疗靶点的确定提供了路线图。