Plener Joshua, Ammendolia Carlo, Hogg-Johnson Sheilah
Division of Graduate Studies, Canadian Memorial Chiropractic College.
Institute for Health Policy Management and Evaluation, University of Toronto.
J Can Chiropr Assoc. 2022 Apr;66(1):74-84.
Degenerative cervical radiculopathy (DCR) is a common condition which, due to the aging global population, is expected to worsen over time. For the majority of patients with DCR, surgical intervention is not required as nonoperative management is sufficient for symptom improvement. However, there are significant gaps within the literature as the majority of past systematic reviews assessing conservative interventions are outdated, or omit relevant studies due to strict inclusion/exclusion criteria. Therefore, an updated understanding of the effectiveness of noninvasive nonoperative management for DCR is required.
We will search MEDLINE, CENTRAL, Embase, PsycINFO, and CINAHL from inception, as well as hand-search reference lists of included studies and previous systematic reviews, to identify peer-reviewed randomized controlled trials on this topic.
The results of this review will provide an understanding of the effectiveness of various nonoperative interventions. The quality of evidence will also be assessed using the GRADE approach.
PROSPERO CRD42021249699.
退行性颈椎神经根病（DCR）是一种常见病症，由于全球人口老龄化，预计其病情会随着时间推移而恶化。对于大多数DCR患者而言，无需手术干预，因为非手术治疗足以改善症状。然而，文献中存在重大空白，因为过去大多数评估保守治疗的系统评价已过时，或者由于严格的纳入/排除标准而遗漏了相关研究。因此，需要对DCR的非侵入性非手术治疗的有效性有更新的认识。
我们将从数据库建立之初开始检索MEDLINE、CENTRAL、Embase、PsycINFO和CINAHL，同时手工检索纳入研究和以往系统评价的参考文献列表，以识别关于该主题的同行评审随机对照试验。
本综述的结果将有助于了解各种非手术治疗的有效性。还将使用GRADE方法评估证据质量。
PROSPERO CRD42021249699。
