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病例报告及文献综述:肺动脉感染性动脉瘤形成——持续性感染的一种罕见但危险的后遗症

A Case Report and Review of the Literature: Infectious Aneurysm Formation in the Pulmonary Arteries-A Rare but Perilous Sequela of Persisting Infection With .

作者信息

Ruwisch Jannik, Fischer Bettina, Häbel Lea, Laenger Florian, Bollmann Benjamin-Alexander

机构信息

Clinic for Respiratory Medicine, Hannover Medical School, Hannover, Germany.

Biomedical Research in End Stage and Obstructive Lung Disease, German Center for Lung Research, Hannover, Germany.

出版信息

Front Microbiol. 2022 May 17;13:893737. doi: 10.3389/fmicb.2022.893737. eCollection 2022.

Abstract

Septic aneurysms of the pulmonary artery are rare conditions, with few cases having been reported worldwide. They are assumed to result from septic emboli that cause a local inflammatory reaction of the arterial wall, ultimately leading to degenerative changes. We report the case of a 63-year-old female patient presenting with urosepsis and first diagnosis of diabetes mellitus, who developed a life-threatening infectious pulmonary artery aneurysm secondary to bacteremia with . The patient required a lobectomy due to pulmonary hemorrhage. We review the clinical hallmarks of related septic pulmonary embolic disease and summarize currently known risk factors for the development of infectious aneurysmatic disease including diabetes mellitus and other states of immunosuppression. The featured case aims to increase the awareness for this seldom but life-threatening complication of infectious diseases such as urosepsis.

摘要

肺动脉脓毒性动脉瘤是罕见病症,全球报道的病例很少。它们被认为是由脓毒性栓子引起的,这些栓子会导致动脉壁发生局部炎症反应,最终导致退行性改变。我们报告了一例63岁女性患者,该患者出现尿脓毒症且首次诊断为糖尿病,继发于菌血症后发展为危及生命的感染性肺动脉动脉瘤。由于肺出血,该患者需要进行肺叶切除术。我们回顾了相关脓毒性肺栓塞疾病的临床特征,并总结了目前已知的感染性动脉瘤疾病的危险因素,包括糖尿病和其他免疫抑制状态。该典型病例旨在提高对尿脓毒症等传染病这种罕见但危及生命的并发症的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8506/9152446/5ee9811f8506/fmicb-13-893737-g0001.jpg

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