School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Med Biol Eng Comput. 2022 Aug;60(8):2189-2199. doi: 10.1007/s11517-022-02596-y. Epub 2022 Jun 3.
Biomechanical effect of posterior intra-articular cages and cantilever technique on the congenital basilar invagination (BI) combined with atlantoaxial dislocation (AAD) was investigated and evaluated using finite element (FE) analysis. A 3D nonlinear occipitocervical segment C0-C3 FE models of congenital BI and AAD was established. Then, the FE model treated with C2 pedicle screw and occipital plate fixation coupled with intra-articular cages (Cage + C2PS + OP) was compared to that without intra-articular cages (C2PS + OP). The range of motion (ROM) of C0C1-C2 and the maximum von Mises stresses (MVMS) on the intra-articular cages, screw-plate system, and C2 endplate were calculated and compared to further analyze the stability of atlantoaxial joint and assess the collapse and fracture risks of intra-articular cages and screw-plate system. ROM of C0C1-C2 segment was reduced by 57.58%, 63.33%, 78.18%, and 75.90%, and the peak stresses of C2 pedicle screw and occipital plate were decreased by 84.86%, 72.90%, 73.24%, and 84.90% and 78.35%, 76.64%, 81.82%, and 89.49% for Cage + C2PS + OP model in flexion, extension, lateral bending, and axial rotation when compared with the C2PS + OP model under the same condition. The MVMS of intra-articular cages were 13.80 MPa, 40.26 MPa, 26.93 MPa, and 17.50 MPa and those of C2 endplate were 14.56 MPa, 34.80 MPa, 36.29 MPa, and 37.56 MPa in Cage + C2PS + OP model under same conditions. Posterior intra-articular cages and cantilever technique to treat BI-AAD can improve the stability of the atlantoaxial joint and reduce the risk of screw-plate breakage. The intra-articular cages can not only complement the height loss on account of atlantooccipital fusion but also provide stable support for posterior fixation fusion.
采用有限元分析方法研究和评估了后关节内笼和悬臂技术对先天性颅底凹陷症(BI)合并寰枢椎脱位(AAD)的生物力学影响。建立了先天性 BI 和 AAD 的三维非线性枕颈节 C0-C3 的有限元模型。然后,将 C2 椎弓根螺钉和枕骨板固定结合关节内笼(Cage+C2PS+OP)治疗的 FE 模型与无关节内笼(C2PS+OP)治疗的 FE 模型进行比较。计算并比较了 C0C1-C2 的活动范围(ROM)和关节内笼、螺钉板系统和 C2 终板的最大 von Mises 应力(MVMS),以进一步分析寰枢关节的稳定性,并评估关节内笼和螺钉板系统的塌陷和骨折风险。与 C2PS+OP 模型相比,C0C1-C2 节段的 ROM 分别降低了 57.58%、63.33%、78.18%和 75.90%,C2 椎弓根螺钉和枕骨板的峰值应力分别降低了 84.86%、72.90%、73.24%和 84.90%和 78.35%、76.64%、81.82%和 89.49%,在相同条件下,Cage+C2PS+OP 模型在屈伸、侧屈和轴向旋转时。在相同条件下,关节内笼的 MVMS 分别为 13.80MPa、40.26MPa、26.93MPa 和 17.50MPa,C2 终板的 MVMS 分别为 14.56MPa、34.80MPa、36.29MPa 和 37.56MPa。后关节内笼和悬臂技术治疗 BI-AAD 可提高寰枢关节的稳定性,降低螺钉板断裂的风险。关节内笼不仅可以弥补寰枕融合造成的高度损失,还可以为后路固定融合提供稳定的支撑。