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酷似肺癌的肺隐球菌病:3例报告

Pulmonary cryptococcosis mimicking lung cancer: 3 case report.

作者信息

Xin Zhifei, Li Bowen, Xue Wenfei, Lin Wei, Zhao Qingtao, Zhang Xiaopeng

机构信息

Hebei General Hospital, Shijiazhuang, Hebei, China.

Hebei General Hospital, Shijiazhuang, Hebei, China; North China University of Science and Technology, Tangshan, Hebei, China.

出版信息

Int J Surg Case Rep. 2022 May;94:106973. doi: 10.1016/j.ijscr.2022.106973. Epub 2022 Apr 1.

DOI:10.1016/j.ijscr.2022.106973
PMID:35658271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9093010/
Abstract

INTRODUCTION AND IMPORTANCE

Pulmonary cryptococcosis is an opportunistic pathogen. However, it is difficult to differentiate it from other diseases by imaging. Therefore, the clinical presentation and imaging features of patients with pulmonary cryptococcosis are analyzed and summarized to improve clinicians' early recognition of the disease.

CASE PRESENTATION

We present a case where preoperative imaging was difficult to differentiate between pulmonary cryptococcosis and non-small cell lung cancer. A pathological biopsy was taken by surgical treatment to clarify the diagnosis.

CLINICAL DISCUSSION

Three cases of Cryptococcus pulmonary patients diagnosed by pathology in our department were analyzed. We believe that the diagnosis should be confirmed as soon as possible through surgery, relevant laboratory tests, and pathological examinations, and antifungal treatment should be carried out in time.

CONCLUSION

We believe that an earlier and clearer diagnosis of pulmonary cryptococcosis requires an earlier interplay of imaging, pathology, testing, and individual patient differences.

摘要

引言与重要性

肺隐球菌病是一种机会性致病菌。然而,通过影像学检查很难将其与其他疾病区分开来。因此,对肺隐球菌病患者的临床表现及影像学特征进行分析总结,以提高临床医生对该病的早期识别。

病例介绍

我们呈现了一例术前影像学检查难以区分肺隐球菌病与非小细胞肺癌的病例。通过手术治疗进行病理活检以明确诊断。

临床讨论

对我科经病理确诊的3例肺隐球菌病患者进行分析。我们认为应通过手术、相关实验室检查及病理检查尽快确诊,并及时进行抗真菌治疗。

结论

我们认为,要更早、更明确地诊断肺隐球菌病,需要影像学、病理学、检测及个体患者差异之间更早的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d82/9093010/d9667b77bace/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d82/9093010/d5bf12016dd6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d82/9093010/d9667b77bace/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d82/9093010/d5bf12016dd6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d82/9093010/d9667b77bace/gr2.jpg

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Clin Chim Acta. 2022 Jan 1;524:78-83. doi: 10.1016/j.cca.2021.11.017. Epub 2021 Nov 27.
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Clinical and Computed Tomography (CT) Characteristics of Pulmonary Nodules Caused by Cryptococcal Infection.隐球菌感染所致肺结节的临床及计算机断层扫描(CT)特征
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Performance of the Lateral Flow Assay and the Latex Agglutination Serum Cryptococcal Antigen Test in Cryptococcal Disease in Patients with and without HIV.
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