Section of Neonatology, Department of Pediatrics Baylor College of Medicine & Texas Children's Hospital Houston, TX 77030, USA.
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA.
Clin Perinatol. 2022 Jun;49(2):485-502. doi: 10.1016/j.clp.2022.02.012. Epub 2022 Apr 21.
Preterm infants are at higher risk of mortality and morbidity compared with those born at term. Nutrition-related morbidities include poor growth, immune deficiency, nutritional deficiencies, and adverse long-term neurodevelopment. In addition to macronutrients, many nutritional supplements have been used to enhance growth and development, and decrease infections. Nutrients can enhance preterm infants' immune status, optimize the microbiome, improve growth and development, and influence the risk of necrotizing enterocolitis, sepsis, and other outcomes.
早产儿与足月儿相比,死亡率和发病率更高。与营养相关的疾病包括生长不良、免疫缺陷、营养缺乏和不良的长期神经发育。除了宏量营养素外,还使用了许多营养补充剂来促进生长发育,减少感染。营养素可以增强早产儿的免疫状态,优化微生物组,促进生长发育,并影响坏死性小肠结肠炎、败血症等结局的风险。