Department of Infectious Diseases, Japanese Red Cross Narita Hospital, 90-1 Iidacho, Narita, Chiba, Japan.
Department of Infectious Diseases, Kameda Medical Center, Kamogawa, Chiba, Japan.
BMC Infect Dis. 2022 Jun 4;22(1):520. doi: 10.1186/s12879-022-07495-z.
Catheter-related bloodstream infection (CRBSI), caused by rapidly growing mycobacteria (RGM), is a rare infectious complication in hematopoietic stem cell transplant (HSCT) recipients and can often be misdiagnosed as Gram-positive rod (GPR) bacteremia.
We present a case of CRBSI caused by Mycobacterium wolinskyi, a rare RGM, in a 44-year-old female patient who received an umbilical cord blood transplant.
Rapidly growing mycobacteria can stain as GPRs and may grow in routine blood culture media after 3-4 days of incubation. These features are not widely known to clinicians, and acid-fast staining is therefore recommended when unidentifiable GPRs are detected in blood cultures, especially in immunocompromised patients, such as those with hematologic malignancies or intravascular devices.
由快速生长分枝杆菌（RGM）引起的导管相关血流感染（CRBSI）是造血干细胞移植（HSCT）受者中一种罕见的感染性并发症，常被误诊为革兰阳性杆菌（GPR）菌血症。
我们报告了一例由罕见的 RGM 沃尔氏分枝杆菌引起的 CRBSI 病例，患者为 44 岁女性，接受了脐带血移植。
快速生长分枝杆菌可被染成 GPR 外观，且在常规血培养 3-4 天后可能在培养物中生长。这些特征不为临床医生广泛知晓，因此当血培养中出现无法识别的 GPR 时，建议进行抗酸染色，特别是在免疫功能低下的患者中，如患有血液系统恶性肿瘤或血管内装置的患者。
