用微生物球体拓展精准肿瘤学工具包，用于早期癌症诊断。

Expanding the precision oncology toolkit with micro-organospheres for early cancer diagnosis.

机构信息

Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY, NY 10065, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, The Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY, NY 10065, USA.

出版信息

Cell Stem Cell. 2022 Jun 2;29(6):873-875. doi: 10.1016/j.stem.2022.05.002.

DOI:10.1016/j.stem.2022.05.002

PMID:35659872

Abstract

Using an automatic microfluidics droplet platform, Ding et al. successfully replicated the tumor micro-environment by generating micro-organospheres, which were then used to predict the response to anti-tumor drugs. These miniature models could be obtained within an extremely short time frame of 14 days, amplifying their role in facilitating cancer treatment decisions.

摘要

利用自动化微流控液滴平台，丁等人成功复制了肿瘤微环境，生成了微器官球，然后用于预测抗肿瘤药物的反应。这些微型模型可以在短短 14 天内获得，这极大地促进了癌症治疗决策。