Traboulsi E I, Jalkh A E, Frangieh G T, Tomb J
Ann Ophthalmol. 1987 Feb;19(2):45-7.
The cytomorphologic findings of a vitrectomy specimen from the right eye of an 80-year-old woman with an unsuspected primary choroidal malignant melanoma are described. The patient had undergone a closed vitrectomy because of chronic vitreous hemorrhage. Histocytology of the vitreous fluid specimens revealed melanoma cells of variable shape and size (from 30-150 microns) with eccentric nuclei. Many of these cells were binucleated or multinucleated with small, uniform, evenly dispersed intracytoplasmic melanin granules. The histocytologic findings together with the postoperative tumor characteristics by ultrasonography and fluorescein angiography suggested the diagnosis of choroidal malignant melanoma.
描述了一名80岁女性右眼玻璃体切除标本的细胞形态学发现，该患者患有未被怀疑的原发性脉络膜恶性黑色素瘤。患者因慢性玻璃体出血接受了闭合式玻璃体切除术。玻璃体液标本的组织细胞学检查显示，黑色素瘤细胞形状和大小各异（30 - 150微米），细胞核偏心。许多细胞为双核或多核，胞质内有小的、均匀且均匀分布的黑色素颗粒。组织细胞学发现以及术后超声检查和荧光素血管造影的肿瘤特征提示为脉络膜恶性黑色素瘤。
