Guerin Eoin, Hiscott Paul, Damato Bertil
Department of Clinical Sciences, Unit of Ophthalmology, University of Liverpool, Liverpool, UK.
Acta Ophthalmol Scand. 2006 Jun;84(3):323-7. doi: 10.1111/j.1600-0420.2005.00630.x.
To examine a series of choroidal melanoma specimens to determine the frequency of overlying choroidal neovascularization (CNV) and to ascertain whether CNV over choroidal malignant melanoma is associated with any particular histological tumour characteristics.
We carried out a retrospective histological analysis of globes containing choroidal melanomas for evidence of choroidal neovascular membranes.
Microscopic evidence of choroidal neovascular membranes was evident in 6% of cases. Choroidal neovascularization was not associated with any particular histological tumour characteristic.
Choroidal neovascularization over choroidal malignant melanoma is not an infrequent occurrence and possibly appears as frequently as CNV over choroidal naevi. The presence of a choroidal neovascular membrane over a pigmented fundal lesion should not be taken as reassurance that the lesion is benign.
检查一系列脉络膜黑色素瘤标本，以确定脉络膜新生血管形成（CNV）的发生率，并确定脉络膜恶性黑色素瘤上的CNV是否与任何特定的组织学肿瘤特征相关。
我们对含有脉络膜黑色素瘤的眼球进行了回顾性组织学分析，以寻找脉络膜新生血管膜的证据。
6%的病例中可见脉络膜新生血管膜的微观证据。脉络膜新生血管形成与任何特定的组织学肿瘤特征均无关联。
脉络膜恶性黑色素瘤上的脉络膜新生血管形成并非罕见，其出现频率可能与脉络膜痣上的CNV相同。色素性眼底病变上存在脉络膜新生血管膜不应被视为该病变为良性的依据。
