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[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation].

作者信息

Bailenger J, Lacassie A

出版信息

Ann Parasitol Hum Comp. 1986;61(6):659-72. doi: 10.1051/parasite/1986616659.

DOI:10.1051/parasite/1986616659
PMID:3566084
Abstract

In order to assess the role of inflammation and its components in spontaneous cure of Strongyloides ratti infestation, rats were treated with non-steroid anti-inflammatory agents (indometacin; sodium salicylate) or with antagonists of certain mediators (dexchlorpheniramin; cyproheptadin, promethazin). Results were compared with those obtained in similar treatments of rats infested by other Nematoda which also give rise to spontaneous cure: especially Trichinella spiralis, and Nippostrongylus brasiliensis. Coordinating the various findings made it possible to devise a pattern accounting for the chain of reactions that lead to rejection of the parasite.

摘要

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