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正电子发射断层磁共振成像在脑肿瘤诊断与治疗中的作用

Role of Molecular Imaging with PET/MR Imaging in the Diagnosis and Management of Brain Tumors.

机构信息

Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.

Department of Neuro Imaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Hosur Road, Bengaluru, Karnataka 560-029, India.

出版信息

PET Clin. 2022 Jul;17(3):431-451. doi: 10.1016/j.cpet.2022.03.002. Epub 2022 May 31.

DOI:10.1016/j.cpet.2022.03.002
PMID:35662494
Abstract

Gliomas are the most common primary brain tumors. Hybrid PET/MR imaging has revolutionized brain tumor imaging, allowing for noninvasive, simultaneous assessment of morphologic, functional, metabolic, and molecular parameters within the brain. Molecular information obtained from PET imaging may aid in the detection, classification, prognostication, and therapeutic decision making for gliomas. F-fluorodeoxyglucose (FDG) has been widely used in the setting of brain tumor imaging, and multiple techniques may be employed to optimize this methodology. More recently, a number of non-F-FDG-PET radiotracers have been applied toward brain tumor imaging and are used in clinical practice.

摘要

神经胶质瘤是最常见的原发性脑肿瘤。杂交 PET/MR 成像技术使脑肿瘤成像发生了革命性变化,可在不进行有创检查的情况下,对脑内的形态、功能、代谢和分子参数进行同步评估。从 PET 成像获得的分子信息有助于脑胶质瘤的检测、分类、预后和治疗决策。氟代脱氧葡萄糖(FDG)已广泛应用于脑肿瘤成像中,可采用多种技术对其进行优化。最近,一些非 F-FDG-PET 放射性示踪剂已应用于脑肿瘤成像,并在临床实践中使用。

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