接种A组链球菌疫苗后发生的淋巴细胞性甲状腺炎。
Lymphoid thyroiditis following immunization with group A streptococcal vaccine.
作者信息
Tonooka N, Leslie G A, Greer M A, Olson J C
出版信息
Am J Pathol. 1978 Sep;92(3):681-90.
Abstract
Severe lymphoid thyroiditis and associated hypothyroidism occurred in all of 7 male and 4 female F(7) derivatives (seventh generation) of rats immunized in each generation against Group A streptococci. This evidence of thyroiditis produced by immunization against a nonthyroidal antigen suggests that some cases of Hashimoto's thyroiditis in humans may result from nonspecific immune responses.
摘要
在每一代都针对A组链球菌进行免疫的大鼠的7只雄性和4只雌性F(7) 代（第七代）后代中，均出现了严重的淋巴细胞性甲状腺炎及相关的甲状腺功能减退。这种由针对非甲状腺抗原的免疫接种所产生的甲状腺炎证据表明，人类的某些桥本甲状腺炎病例可能是由非特异性免疫反应所致。
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