Verlinden Justin J, Moloney Mairead E, Whitehurst Lauren N, Weafer Jessica
Department of Psychology, University of Kentucky, Lexington, KY, United States.
Department of Sociology, University of Kentucky, Lexington, KY, United States.
Front Behav Neurosci. 2022 May 19;16:875168. doi: 10.3389/fnbeh.2022.875168. eCollection 2022.
Alcohol Use Disorder (AUD) and insomnia are highly comorbid; at least 40% of individuals with AUD suffer from insomnia. Women are more likely to report insomnia than men and have seen a concerning rise in rates of AUD in recent years. As such, the association between AUD and insomnia could be particularly pronounced in women. However, currently little is known regarding sex differences in this association. Here we examined the degree to which relationships between alcohol use and sleep quality differ between women and men.
Heavy drinking women ( = 66) and men ( = 45) completed the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality and the Alcohol Use Disorders Identification Test (AUDIT) to assess alcohol use and alcohol-related problems. Hierarchical regression analyses were conducted to determine sex differences in the association between poor sleep quality and alcohol-related problems.
After controlling for age, global subjective stress, and depression, sex significantly moderated the positive association between poor sleep quality and alcohol-related problems. Further analyses of the simple slopes for each sex revealed that poorer sleep quality (i.e., higher scores on the PSQI) were associated with greater alcohol-related problems (i.e., higher scores on the AUDIT) in women, but not in men.
These results suggest that in heavy drinkers with insomnia, poor sleep is more strongly associated with drinking problems in women than in men. Future research is needed to investigate potential mechanisms underlying this relationship. Specifically, it will be important to determine whether sleep problems in heavy drinking women are a cause or consequence, or both, of heavy drinking.
酒精使用障碍(AUD)与失眠高度共病;至少40%的酒精使用障碍患者患有失眠。女性比男性更有可能报告失眠,且近年来酒精使用障碍的发病率呈令人担忧的上升趋势。因此,酒精使用障碍与失眠之间的关联在女性中可能尤为明显。然而,目前对于这种关联中的性别差异知之甚少。在此,我们研究了酒精使用与睡眠质量之间的关系在女性和男性中存在差异的程度。
重度饮酒女性(n = 66)和男性(n = 45)完成匹兹堡睡眠质量指数(PSQI)以评估睡眠质量,完成酒精使用障碍识别测试(AUDIT)以评估酒精使用及与酒精相关的问题。进行分层回归分析以确定睡眠质量差与酒精相关问题之间关联的性别差异。
在控制年龄、总体主观压力和抑郁后,性别显著调节了睡眠质量差与酒精相关问题之间的正相关。对每种性别的简单斜率进一步分析表明,睡眠质量较差(即PSQI得分较高)与女性中更严重的酒精相关问题(即AUDIT得分较高)相关,但在男性中并非如此。
这些结果表明,在患有失眠的重度饮酒者中,睡眠质量差与女性饮酒问题的关联比男性更强。未来需要进行研究以调查这种关系背后的潜在机制。具体而言,确定重度饮酒女性的睡眠问题是重度饮酒的原因、后果还是两者皆是将很重要。