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中年至晚年饮酒与睡眠之间关联的性别差异。

Sex differences in associations between alcohol use and sleep in mid-to-late life.

机构信息

Department of Psychological Sciences, University of Missouri, 210 McAlester Hall, Columbia, MO, 65211, USA.

Department of Psychological Sciences, University of Missouri, 210 McAlester Hall, Columbia, MO, 65211, USA; Department of Psychiatry, University of Missouri, 1 Hospital Dr, Columbia, MO, 65212, USA.

出版信息

Sleep Med. 2022 Dec;100:298-303. doi: 10.1016/j.sleep.2022.08.016. Epub 2022 Sep 2.

Abstract

OBJECTIVES

To examine associations between alcohol use and sleep in middled-aged/older adults and to test sex as a moderator of this relationship.

METHODS

Participants were 183 adults (46% female) ages 50 and above who consumed alcohol in the past year. Linear regressions tested sex as a moderator of associations between alcohol use and sleep parameters. Alcohol use was measured using the Alcohol Use Disorders Identification Test (AUDIT). Overall sleep health and sleep quality were assessed using the Pittsburgh Sleep Quality Index (PSQI), and pre-sleep arousal was assessed using the Pre-Sleep Arousal Scale.

RESULTS

Overall, 11% of participants screened positive for hazardous drinking (AUDIT scores of 7+/8+ for women/men), and 59% reported poor overall sleep health (scores >5 on the PSQI). Alcohol use was not associated with overall sleep health (B = -0.25, p = .08) or pre-sleep arousal (B = 0.15, p = .64). However, contrary to hypotheses, more hazardous drinking was associated with better subjective sleep quality, only among women (B = -0.08, p = .009). Alcohol use was not associated with sleep quality among men (B = 0.01, p = .58). Associations remained significant when controlling for age, symptoms of anxiety and depression, body mass index, use of sleep medication, number of medical conditions, and chronic pain.

CONCLUSIONS

Among middle-aged and older adults, alcohol use is more strongly associated with sleep patterns among women than men, when assessed concurrently (i.e., at the same time point). Findings support the need for further consideration of sex differences in associations between alcohol use and sleep.

摘要

目的

研究中年/老年成年人的饮酒与睡眠之间的关联,并检验性别是否是这种关系的调节因素。

方法

参与者为 183 名年龄在 50 岁及以上、过去一年有饮酒行为的成年人(女性占 46%)。线性回归检验了性别对饮酒与睡眠参数之间关系的调节作用。使用酒精使用障碍识别测试(AUDIT)测量饮酒行为。使用匹兹堡睡眠质量指数(PSQI)评估整体睡眠健康和睡眠质量,使用睡前觉醒量表(Pre-Sleep Arousal Scale)评估睡前觉醒。

结果

总体而言,11%的参与者筛查出有危险饮酒行为(女性 AUDIT 得分为 7+/8+,男性为 7+/8+),59%报告整体睡眠健康状况较差(PSQI 得分>5)。饮酒行为与整体睡眠健康(B=-0.25,p=0.08)或睡前觉醒(B=0.15,p=0.64)无关。然而,与假设相反,更危险的饮酒行为与女性的主观睡眠质量更好相关(B=-0.08,p=0.009),而与男性无关(B=0.01,p=0.58)。当控制年龄、焦虑和抑郁症状、体重指数、睡眠药物使用、疾病数量和慢性疼痛等因素时,这些关联仍然显著。

结论

在中年和老年成年人中,与男性相比,当同时评估(即在同一时间点评估)时,饮酒行为与女性的睡眠模式之间的关联更为密切。这些发现支持需要进一步考虑性别差异在饮酒与睡眠之间的关联。

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