Ward Kayla, Krishnan Anirudh, R Iyengar Krishnan, Robertson Thomas, White Richard, Urkude Ravindra
Neurology Department, Gold Coast Hospital and Health Service, Southport, Queensland, Australia.
Neurology Department, Townsville Hospital and Health Service, Townsville, Queensland, Australia.
BMJ Neurol Open. 2022 May 18;4(1):e000290. doi: 10.1136/bmjno-2022-000290. eCollection 2022.
is an exceedingly rare cause of parasitic myositis endemic to Australia, more specifically, Tasmania and North Queensland. There is a paucity of literature regarding this diagnosis, with only nine previously described cases.
This report details two cases of biopsy-confirmed myositis from Townsville University Hospital and describes the first-ever case of subclinical infection. There is limited known information regarding the life cycle and a definitive host which has hindered the development of a non-invasive diagnostic test. A review of the previously described cases has identified the hallmark features of this enigmatic condition: a triad of serological markers including deranged hepatic function, persistent eosinophilia and an elevated creatine kinase.
This report aimed to raise awareness of myositis and the possibility of subclinical infection, which suggests a protracted disease course. Further research is required to identify a non-invasive diagnostic test, given that early diagnosis and timely initiation of albendazole treatment may drastically limit patient disability.
是一种极为罕见的寄生虫性肌炎病因，在澳大利亚流行，更具体地说，在塔斯马尼亚和北昆士兰。关于这一诊断的文献很少，此前仅有9例病例描述。
本报告详细介绍了汤斯维尔大学医院经活检确诊的两例肌炎病例，并描述了首例亚临床感染病例。关于其生命周期和终宿主的已知信息有限，这阻碍了非侵入性诊断测试的开发。对先前描述病例的回顾确定了这种神秘病症的标志性特征：一组血清学标志物，包括肝功能紊乱、持续性嗜酸性粒细胞增多和肌酸激酶升高。
本报告旨在提高对肌炎和亚临床感染可能性的认识，这表明病程较长。鉴于早期诊断和及时开始使用阿苯达唑治疗可能会极大地限制患者的残疾程度，因此需要进一步研究以确定非侵入性诊断测试。
