Dennett X, Siejka S J, Andrews J R, Beveridge I, Spratt D M
State Neuropathology Service, Department of Pathology, University of Melbourne, VIC.
Med J Aust. 1998 Mar 2;168(5):226-7. doi: 10.5694/j.1326-5377.1998.tb140136.x.
We report two patients who presented with increasing malaise and myalgia, and had biopsy-proven polymyositis. Their conditions deteriorated after corticosteroid treatment, and repeat muscle biopsies showed adult and larval nematodes. Anthelminthic treatment was completely successful in both cases. The infecting nematode appears to belong to a new genus and is, to our knowledge, the first known muspiceoid nematode to infect humans. Its life cycle and the route of infection are unknown.
我们报告了两名患者,他们表现出日益加重的不适和肌痛,经活检证实患有多发性肌炎。在接受皮质类固醇治疗后,他们的病情恶化,再次进行肌肉活检显示存在成虫和幼虫线虫。抗蠕虫治疗在这两个病例中均取得了完全成功。感染的线虫似乎属于一个新属,据我们所知,它是已知的首例感染人类的似肌线虫。其生命周期和感染途径尚不清楚。