利用基于 PCR 的测序诊断澳大利亚人类肌炎病例中的 Haycocknema perplexum 感染。
Using PCR-Based Sequencing to Diagnose Haycocknema perplexum Infection in Human Myositis Case, Australia.
出版信息
Emerg Infect Dis. 2018 Dec;24(12):2368-2370. doi: 10.3201/eid2412.181240.
Abstract
We report a case of myositis in a male patient in Australia who had progressive weakness and wasting in his left lower limb. Although clinical, pathologic, and laboratory assessments were inconclusive, a new, nested PCR-coupled sequencing method enabled the unequivocal diagnosis of myositis caused by the enigmatic nematode Haycocknema perplexum.
摘要
我们报告了一例在澳大利亚的男性患者的肌炎病例，他的左下肢逐渐出现无力和消瘦。尽管临床、病理和实验室评估没有明确结论，但一种新的嵌套 PCR 结合测序方法能够明确诊断出由神秘线虫 Haycocknema perplexum 引起的肌炎。
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引用本文的文献
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本文引用的文献
1
Haycocknema perplexum: an emerging cause of parasitic myositis in Australia.哈氏线虫（Haycocknema perplexum）：澳大利亚寄生虫性肌炎的一个新出现病因。
Commun Dis Intell Q Rep. 2016 Dec 24;40(4):E496-E499. doi: 10.33321/cdi.2016.40.55.
2
More parasitic myositis cases in humans in Australia, and the definition of genetic markers for the causative agents as a basis for molecular diagnosis.澳大利亚人类中更多的寄生虫性肌炎病例，以及将病原体的遗传标记定义作为分子诊断的基础。
Infect Genet Evol. 2016 Oct;44:69-75. doi: 10.1016/j.meegid.2016.06.026. Epub 2016 Jun 14.
3
A further patient with parasitic myositis due to Haycocknema perplexum, a rare entity.另一位寄生虫性肌炎患者是由罕见的海克线虫引起的。
J Clin Neurosci. 2013 Jul;20(7):1019-22. doi: 10.1016/j.jocn.2012.08.009. Epub 2013 May 7.
4
Parasitic myositis in tropical Australia.热带澳大利亚的寄生虫性肌炎
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5
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Haycocknema perplexum n. g., n. sp. (Nematoda: Robertdollfusidae): an intramyofibre parasite in man.perplexum海氏线虫新属新种（线虫纲：罗氏线虫科）：人体肌纤维内寄生虫
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