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非重症胆源性胰腺炎患者腹腔镜胆囊切除术的时机选择。

Timing of laparoscopic cholecystectomy in patients with non-severe biliary pancreatitis.

作者信息

Şenol Serdar Şenol, Polat Cafer

机构信息

Department of General Surgery, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.

出版信息

Prz Gastroenterol. 2022;17(2):110-115. doi: 10.5114/pg.2022.116375. Epub 2022 May 19.

Abstract

INTRODUCTION

In patients with acute biliary pancreatitis (ABP), cholecystectomy is mandatory to prevent further biliary events, but the precise timing of laparoscopic cholecystectomy (LC) for non-severe disease remain a subject of ongoing debate.

AIM

To prove which method - early or delayed LC - is the method of choice in the non-severe disease by examining rates of gallstone-related complications, dissection difficulty, conversion rate, morbidity, mortality, and length of hospital stay.

MATERIAL AND METHODS

We retrospectively analysed the data of patients diagnosed with non-severe ABP, who were followed and underwent LC in our department. Patients who met the inclusion criteria were divided in to the early (< 2 weeks) and the delayed groups (> 2 weeks).

RESULTS

The patients in the early and delayed groups ( = 43/39) were similar in terms of demographic characteristics, comorbidities, and severity of biliary pancreatitis. The mean time to surgery was 1.7 vs. 6.5 weeks in the early and late groups, respectively. Patients in the delayed group had a 17.9% readmission rate. The causes were acute pancreatitis (10.2%), cholangitis, and cholecystitis. The conversion and the difficult dissection rates were 11.6% vs. 12.8% and 13.95% vs. 20.51% in the early and delayed groups, respectively. Mortality was not observed in the groups. Morbidity rates were 4.6% vs. 5%, and mean length of hospital stay was 10 vs. 17 days in the early and delayed groups, respectively.

CONCLUSIONS

Delayed LC increases the rate of biliary events and early LC does not increase the operative difficulty or morbidity in patients with ABP.

摘要

引言

在急性胆源性胰腺炎(ABP)患者中,胆囊切除术对于预防进一步的胆道事件是必要的,但对于非重症疾病行腹腔镜胆囊切除术(LC)的确切时机仍存在争议。

目的

通过检查胆石相关并发症发生率、解剖难度、中转率、发病率、死亡率和住院时间,证明早期或延迟LC哪种方法是治疗非重症疾病的首选方法。

材料与方法

我们回顾性分析了在我院接受随访并进行LC的非重症ABP患者的数据。符合纳入标准的患者分为早期组(<2周)和延迟组(>2周)。

结果

早期组和延迟组患者(n = 43/39)在人口统计学特征、合并症和胆源性胰腺炎严重程度方面相似。早期组和晚期组的平均手术时间分别为1.7周和6.5周。延迟组患者的再入院率为17.9%。原因是急性胰腺炎(10.2%)、胆管炎和胆囊炎。早期组和延迟组的中转率和困难解剖率分别为11.6%对12.8%和13.95%对20.51%。两组均未观察到死亡病例。早期组和延迟组的发病率分别为4.6%对5%,平均住院时间分别为10天对17天。

结论

延迟LC会增加胆道事件发生率,而早期LC不会增加ABP患者的手术难度或发病率。

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