Damianakis Emmanouil I, Benetos Ioannis S, Evangelopoulos Dimitrios Stergios, Kotroni Aikaterini, Vlamis John, Pneumaticos Spyridon G
Physical Medicine and Rehabilitation, KAT Hospital, Athens, GRC.
3rd Department of Orthopaedic Surgery, National and Kapodistrian University of Athens (NKUA) School of Medicine, KAT Hospital, Athens, GRC.
Cureus. 2022 Apr 28;14(4):e24575. doi: 10.7759/cureus.24575. eCollection 2022 Apr.
Spinal cord injury (SCI) remains an incurable, life-changing neurological condition, causing permanent loss of motor and sensory function in millions of people worldwide and affecting them in every aspect of their personal and social life. In the last two decades, after its success in various fields of medicine, stem cell therapy has been investigated in the research field as a potential treatment for SCI. This review focuses on the pathophysiology of SCI, the characteristics of the different stem cell therapies used for its treatment, and the results of these therapies in recently published clinical trials.
脊髓损伤（SCI）仍然是一种无法治愈、改变人生的神经疾病，导致全球数百万人永久性丧失运动和感觉功能，并在他们个人和社会生活的各个方面影响着他们。在过去二十年中，干细胞疗法在医学各个领域取得成功后，作为SCI的一种潜在治疗方法在研究领域得到了研究。本综述重点关注SCI的病理生理学、用于其治疗的不同干细胞疗法的特点，以及这些疗法在最近发表的临床试验中的结果。
