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Juvenile Alzheimer's disease with cerebellar involvement.

作者信息

Vakili S T, Muller J

出版信息

Arch Pathol Lab Med. 1987 May;111(5):480-2.

PMID:3566478
Abstract

We describe a sporadic case of Alzheimer's disease with cerebellar involvement in a man, who died at age 32 years after an illness lasting seven years, which was marked by progressive dementia and ataxia. The brain was quite atrophic and showed numerous senile plaques of all types and neurofibrillary tangles in the cerebral cortex with some involvement of the basal ganglia and diencephalon. There was cerebellocortical atrophy with numerous large, kurulike plaques. In addition, widespread severe congophilic angiopathy was noted.

摘要

相似文献

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Juvenile Alzheimer's disease with cerebellar involvement.
Arch Pathol Lab Med. 1987 May;111(5):480-2.
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Increased tau accumulation in senile plaques as a hallmark in Alzheimer's disease.老年斑中tau蛋白积累增加是阿尔茨海默病的一个标志。
Am J Pathol. 1989 Jun;134(6):1365-71.
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Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease.β-蛋白淀粉样物质广泛分布于阿尔茨海默病患者的中枢神经系统中。
Am J Pathol. 1989 Feb;134(2):243-51.
4
Microglia in cerebellar plaques in Alzheimer's disease.
Acta Neuropathol. 1990;80(5):493-8. doi: 10.1007/BF00294609.
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Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer's disease.
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