Sanyaolu Adekunle, Marinkovic Aleksandra, Prakash Stephanie, Haider Nafees, Williams Martina, Okorie Chuku, Badaru Olanrewaju, Smith Stella
Department of Public Health, Federal Ministry of Health, Abuja 0000, Nigeria.
Department of Basic Sciences, Saint James School of Medicine, The Valley 0000, Anguilla.
World J Virol. 2022 May 25;11(3):137-143. doi: 10.5501/wjv.v11.i3.137.
Omicron, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant that is now spreading across the world, is the most altered version to emerge so far, with mutations comparable to changes reported in earlier variants of concern linked with increased transmissibility and partial resistance to vaccine-induced immunity. This article provides an overview of the SARS-CoV-2 variant Omicron (B.1.1.529) by reviewing the literature from major scientific databases. Although clear immunological and clinical data are not yet available, we extrapolated from what is known about mutations present in the Omicron variant of SARS-CoV-2 and offer preliminary indications on transmissibility, severity, and immune escape through existing research and databases.
奥密克戎是目前正在全球传播的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）变体，是迄今为止出现的变异程度最大的版本，其突变情况与此前出现的、与传播性增加及对疫苗诱导免疫产生部分抗性相关的关注变体中所报告的变化相当。本文通过回顾主要科学数据库中的文献，对SARS-CoV-2变体奥密克戎（B.1.1.529）进行了概述。尽管目前尚无明确的免疫学和临床数据，但我们根据已知的SARS-CoV-2奥密克戎变体中的突变情况进行推断，并通过现有研究和数据库对其传播性、严重性和免疫逃逸情况给出初步迹象。
