Sanyaolu Adekunle, Marinkovic Aleksandra, Prakash Stephanie, Balendra Vyshnavy, Hamdy Kareem, Haider Nafees, Abbasi Abu Fahad, Hosein Zaheeda, Younis Kokab, Smith Stella, Badaru Olanrewaju, Izurieta Ricardo
D'Youville University, Buffalo, NY USA.
Federal Ministry of Health, Abuja, Nigeria.
Indian J Microbiol. 2024 Dec;64(4):1416-1424. doi: 10.1007/s12088-024-01238-1. Epub 2024 Mar 27.
This article aimed to review the current literature on the impact of continuous shedding of the COVID-19 virus in infected patients in relation to disease outcome variables and viral dynamics. Electronic databases PubMed, Google Scholar, and MedlinePlus were searched using relevant keywords, restricting the selection to thirty-two peer-reviewed articles and four gray literatures from the WHO websites. Findings from this study showed that several variables such as sex, age, immune status, treatments, and vaccines were found to affect the outcomes associated with the COVID-19 virus shedding. These findings highlight the need for further research using longitudinal whole-genome sequencing of the virus and its variants to increase the understanding.
本文旨在综述当前关于新冠病毒感染患者持续排毒对疾病结局变量和病毒动态影响的文献。使用相关关键词检索了电子数据库PubMed、谷歌学术和MedlinePlus，将选择范围限制为32篇同行评议文章和来自世界卫生组织网站的4篇灰色文献。本研究结果表明，性别、年龄、免疫状态、治疗方法和疫苗等几个变量被发现会影响与新冠病毒排毒相关的结局。这些发现凸显了利用病毒及其变体的纵向全基因组测序进行进一步研究以增进理解的必要性。
