McCafferty Jonathan A, Free Matthew D, De Villiers Daniel J, Keith Prue P A
Department of Orthopaedics, Northeast Health Wangaratta, Wangaratta, Victoria, Australia.
J Surg Case Rep. 2022 May 25;2022(5):rjac157. doi: 10.1093/jscr/rjac157. eCollection 2022 May.
In patients presenting with symptomatic bone metastases, the usual primary malignancies are breast, prostate, thyroid, lung and kidney. Pancreatic cancers are an uncommon cause of bone metastasis and, when they are, it is typically to the axial skeleton. We present the case of a 77-year-old woman who presented to our emergency department with right arm pain. Investigation demonstrated a metastatic lesion with impending pathological fracture. Further investigation found a necrotic pancreatic mass in the tail of the pancreas. Histopathology from the humeral metastasis was consistent with metastatic adenosquamous carcinoma of pancreatic origin. The humerus metastasis was successfully managed with an intramedullary nail. This case highlights an unusual presentation of pancreatic adenocarcinoma with humeral bone metastasis.
在出现有症状骨转移的患者中，常见的原发恶性肿瘤是乳腺癌、前列腺癌、甲状腺癌、肺癌和肾癌。胰腺癌是骨转移的罕见原因，即便发生骨转移，通常也是转移至中轴骨骼。我们报告一例77岁女性患者，她因右臂疼痛前来我院急诊科就诊。检查发现有一个转移性病灶，即将发生病理性骨折。进一步检查发现胰腺尾部有一个坏死性肿块。肱骨转移灶的组织病理学检查结果与胰腺来源的转移性腺鳞癌一致。通过髓内钉成功治疗了肱骨转移灶。该病例突出了胰腺腺癌伴肱骨骨转移的一种不寻常表现。
