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围手术期营养的未解决问题:叙述性综述。

Unresolved issues in perioperative nutrition: A narrative review.

机构信息

Human Nutrition Research Unit, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, Canada.

Department of General, Visceral and Oncological Surgery, Klinikum St. Georg, Leipzig, Germany.

出版信息

Clin Nutr. 2022 Jul;41(7):1578-1590. doi: 10.1016/j.clnu.2022.05.015. Epub 2022 May 23.

Abstract

Surgical patients are at an increased risk of negative outcomes if they are malnourished or at risk of malnutrition preoperatively. Optimisation of nutritional status should be a focus throughout the perioperative continuum to promote improved surgical outcomes. Enhanced Recovery after Surgery (ERAS) protocols are increasingly applied in the surgical setting but are not yet widespread. This narrative review focused on areas of perioperative nutrition that are perceived as controversial or are lacking in agreement. A search for available literature was conducted on 1 March 2022 and relevant high-quality articles published since 2015 were considered for inclusion. Most malnutrition screening tools are not specific to the surgical population except for the Perioperative Nutrition Screen (PONS) although more large-scale initiatives are needed to improve the prevalence of preoperative nutrition screening. Poor muscle health is common in patients with malnutrition and further exacerbates negative health outcomes indicating that prevention, detection and treatment is of high importance in this population. Although a lack of consensus remains for who should receive preoperative nutritional therapy, evidence suggests a positive impact on muscle health. Additionally, postoperative nutritional support benefits surgical outcomes, with some patients requiring enteral and/or parenteral feeding routes and showing benefit from immunonutrition. The importance of nutrition extends beyond the time in hospital and should remain a priority post-discharge. The impact of individual or personalised nutrition based on select patient characteristics remains to be further investigated. Overall, the importance of perioperative nutrition is evident in the literature despite select ongoing areas of contention.

摘要

如果外科患者术前存在营养不良或有发生营养不良的风险,他们的不良预后风险将会增加。在围手术期连续护理中,优化营养状况应作为重点,以促进手术结局的改善。加速康复外科(ERAS)方案在外科领域的应用越来越广泛,但尚未普及。本综述重点关注围手术期营养方面存在争议或尚未达成共识的领域。我们于 2022 年 3 月 1 日进行了文献检索,纳入了自 2015 年以来发表的相关高质量文章。除围手术期营养筛查(PONS)外,大多数营养不良筛查工具都不适用于外科人群,尽管需要更多的大规模举措来提高术前营养筛查的普及率。营养不良患者的肌肉健康状况普遍较差,这进一步加重了不良健康结局,表明在这一人群中预防、检测和治疗至关重要。尽管谁应该接受术前营养治疗仍存在共识,但有证据表明这对肌肉健康有积极影响。此外,术后营养支持有益于手术结局,一些患者需要肠内和/或肠外喂养途径,并从免疫营养中获益。营养的重要性不仅限于住院期间,出院后也应继续重视。基于特定患者特征的个体化或个性化营养的影响仍有待进一步研究。总的来说,尽管存在一些持续存在的争议,但围手术期营养的重要性在文献中是显而易见的。

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