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营养不良的手术患者:围手术期结局中的无声流行病?

The malnourished surgery patient: a silent epidemic in perioperative outcomes?

机构信息

Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.

Department of Intensive Care, Erasmus MC, Erasmus University, Rotterdam, Netherlands.

出版信息

Curr Opin Anaesthesiol. 2019 Jun;32(3):405-411. doi: 10.1097/ACO.0000000000000722.

Abstract

PURPOSE OF REVIEW

As many as two of every three major surgery patients are malnourished preoperatively - a diagnosis rarely made and treated even less frequently. Unfortunately, perioperative malnutrition is perhaps the least often identified surgical risk factor and is among the most treatable to improve outcomes.

RECENT FINDINGS

Two important perioperative nutrition guidelines were published recently. Both emphasize nutrition assessment as an essential component of preoperative screening. The recently published perioperative nutrition screen (PONS) readily identifies patients at malnutrition risk, allowing for preoperative nutritional optimization. The use of computerized tomography scan and ultrasound lean body mass (LBM) evaluation to identify sarcopenia associated with surgical risk and guide nutrition intervention is garnering further support. Preoperative nutrition optimization in malnourished patients, use of immunonutrition in all major surgery, avoidance of preoperative fasting, inclusion of postoperative high-protein nutritional supplements, and early postoperative oral intake have all recently been shown to improve outcomes and should be utilized.

SUMMARY

The recent publication of new surgical nutrition guidelines, the PONS score, and use of LBM assessments will allow better identification and earlier intervention on perioperative malnutrition. It is essential that in the future no patient undergoes elective surgery without nutrition screening and nutrition intervention when malnutrition risk is identified.

摘要

目的综述

多达每三个大手术患者中的两个术前存在营养不良——这一诊断很少做出,治疗也很少进行。不幸的是,围手术期营养不良可能是最不常被识别的手术风险因素,也是最可通过治疗来改善结局的因素之一。

最近的发现

最近发布了两项重要的围手术期营养指南。两者都强调营养评估是术前筛查的重要组成部分。最近发布的围手术期营养筛查(PONS)可以轻松识别存在营养不良风险的患者,从而进行术前营养优化。使用计算机断层扫描和超声瘦体重(LBM)评估来识别与手术风险相关的肌肉减少症并指导营养干预措施,正得到更多的支持。在营养不良患者中进行术前营养优化、在所有大手术中使用免疫营养、避免术前禁食、术后补充高蛋白营养补充剂以及术后早期口服摄入,最近均已被证明可改善结局,应加以利用。

总结

新的外科营养指南、PONS 评分以及 LBM 评估的使用,将能够更好地识别和更早地干预围手术期营养不良。未来,任何接受择期手术的患者,如果存在营养不良风险,都必须进行营养筛查和干预,这一点至关重要。

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