MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing Forestry University, Beijing 100083, PR China.
GuangXi Key Laboratory of Chemistry and Engineering of Forest Products, College of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530006, PR China.
Int J Biol Macromol. 2022 Aug 1;214:91-99. doi: 10.1016/j.ijbiomac.2022.05.196. Epub 2022 Jun 3.
To improve the mechanical strength of borax-crosslinked fenugreek galactomannan hydrogels and broaden the application field of galactomannan-based hydrogels, fenugreek galactomannan (FG) was esterified via octenyl succinic anhydride (OSA), and the parameters affecting the esterification reaction were systematically studied. The optimum process for OSA-modified FG (OFG) was as follows: FG concentration 1.5 wt%, n (OSA): n (FG) = 2, n (4-dimethylamino-pyridine, DMAP): n (FG) = 4, and reaction time 12 h. Under this condition, the degree of substitution (DS) was 0.31, and the product yield was 115.05 %. Characterization of FT-IR, H NMR, and HPLC confirmed that the OSA group was successfully introduced into the FG skeleton. The mechanical strength of borax crosslinked OFG hydrogel (OFGH) is 18 times higher than that of FG hydrogel. OFGH shows excellent self-healing, injectable properties and electrical conductivity. This will further expand the application of borax crosslinked galactomannan-based hydrogels in the fields of sensors, drug delivery, and wound dressing.
为了提高硼砂交联胡芦巴半乳甘露聚糖水凝胶的机械强度并拓宽半乳甘露聚糖水凝胶的应用领域，通过辛烯基琥珀酸酐（OSA）对胡芦巴半乳甘露聚糖（FG）进行酯化，系统研究了影响酯化反应的参数。OSA 改性 FG（OFG）的最佳工艺条件为：FG 浓度 1.5wt%，n（OSA）：n（FG）=2，n（4-二甲氨基吡啶，DMAP）：n（FG）=4，反应时间 12h。在此条件下，取代度（DS）为 0.31，产率为 115.05%。FT-IR、H NMR 和 HPLC 的表征证实了 OSA 基团成功引入 FG 骨架。硼砂交联 OFG 水凝胶（OFGH）的机械强度比 FG 水凝胶高 18 倍。OFGH 表现出优异的自修复、可注射性和导电性。这将进一步扩大硼砂交联半乳甘露聚糖基水凝胶在传感器、药物输送和伤口敷料等领域的应用。
