Central Molecular Laboratory, Govind Ballabh Pant, Postgraduate Institute of Medical, Education and Research (GIPMER), New Delhi 110002, India.
Central Molecular Laboratory, Govind Ballabh Pant, Postgraduate Institute of Medical, Education and Research (GIPMER), New Delhi 110002, India; Department of Biochemistry, Govind Ballabh Pant, Postgraduate Institute of Medical, Education and Research (GIPMER), New Delhi 110002, India.
Clin Chim Acta. 2022 Jul 1;532:95-114. doi: 10.1016/j.cca.2022.05.029. Epub 2022 Jun 3.
Cancer remains a common health issue having significant socioeconomic burden worldwide. Despite the awareness campaigns, cancer cases continue to increase due to an aging population and lack of early detection biomarkers. Accordingly, much research has focused on non-traditional approaches which include novel imaging modalities and liquid biopsy. In addition, a considerable number of biomacromolecules as well as other biomarkers have been identified to further explore their potential use as diagnostic, prognostic and therapeutic tools. In this review, we provide an update on these new findings and explore their clinical application in cancer.
癌症仍然是一个常见的健康问题，在全球范围内造成了重大的社会经济负担。尽管开展了宣传活动，但由于人口老龄化和缺乏早期检测生物标志物，癌症病例仍在继续增加。因此，许多研究都集中在非传统方法上，包括新型成像方式和液体活检。此外，已经确定了相当数量的生物大分子以及其他生物标志物，以进一步探索它们作为诊断、预后和治疗工具的潜力。在这篇综述中，我们提供了这些新发现的最新信息，并探讨了它们在癌症中的临床应用。
