TREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
The Kirby Institute, UNSW Sydney, Sydney, Australia.
AIDS Behav. 2022 Dec;26(12):3862-3877. doi: 10.1007/s10461-022-03714-5. Epub 2022 Jun 6.
Despite the mental health and substance use burden among people living with HIV (PLHIV) in the Asia-Pacific, data on their associations with HIV clinical outcomes are limited. This cross-sectional study of PLHIV at five sites assessed depression and substance use using PHQ-9 and ASSIST. Among 864 participants, 88% were male, median age was 39 years, 97% were on ART, 67% had an HIV viral load available and < 1000 copies/mL, 19% had moderate-to-severe depressive symptoms, and 80% had ever used at least one substance. Younger age, lower income, and suboptimal ART adherence were associated with moderate-to-severe depressive symptoms. Moderate-to-high risk substance use, found in 62% of users, was associated with younger age, being male, previous stressors, and suboptimal adherence. Our findings highlight the need for improved access to mental health and substance use services in HIV clinical settings.
尽管亚太地区艾滋病毒感染者（PLHIV）存在心理健康和物质使用问题，但有关这些问题与 HIV 临床结局之间关联的数据有限。本项在五个地点开展的 PLHIV 横断面研究采用 PHQ-9 和 ASSIST 评估抑郁和物质使用情况。在 864 名参与者中，88%为男性，中位年龄为 39 岁，97%正在接受抗逆转录病毒治疗（ART），67%的人有 HIV 病毒载量检测结果且＜1000 拷贝/毫升，19%有中重度抑郁症状，80%的人至少使用过一种物质。年龄较小、收入较低和 ART 依从性欠佳与中重度抑郁症状相关。在 62%的使用者中发现了中高度风险的物质使用，其与年龄较小、男性、既往压力源和 ART 依从性欠佳相关。研究结果强调了在 HIV 临床环境中需要改善获取心理健康和物质使用服务的机会。
