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近期 COVID-19 感染患者髋关节合并感染性关节炎和股骨头无菌性坏死:一个警示性报告。

Concomitant septic arthritis of the hip joint and femoral head avascular necrosis in patients with recent COVID-19 infection: a cautionary report.

机构信息

Joint Reconstruction Research Centre, Tehran University of Medical Sciences, End of Keshavarz Blvd, Tehran, 1419733141, Iran.

Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Department of Radiology, Medical Imaging Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Orthop Surg Res. 2022 Jun 6;17(1):302. doi: 10.1186/s13018-022-03192-4.

Abstract

PURPOSE

At present, concomitant avascular necrosis (AVN) of femoral head and septic arthritis (SA) as a sequel of COVID-19 infection has yet not been documented. By large-scale use of life-saving corticosteroids (CS) in COVID-19 cases, our aim is to warn of the occurrence of hip joint infection in these patients.

METHODS

We report a series of five cases in which patients developed septic arthritis concomitant with AVN after being treated for COVID-19 infection. The mean dose of prednisolone used in these cases was 1695.2 mg. The time period of onset of hip symptoms in our cases from the beginning of the COVID-19 infection was 56 days in the first case, 43 days in the second case, 30 days in the third case, 29 days in the fourth case and 50 days in the last case, with an average time of 41.6 days. All patients underwent surgery depending on the extent of articular cartilage damage by direct anterior approach.

RESULTS

Clinical and laboratory symptoms improved significantly in all patients. The mean visual analogue pain score of the patients decreased from 9.4 (9-10) before surgery to 2.8 (1-4) after 1 week of operation.

CONCLUSION

In any patient with the history of COVID-19 infection specially those who have been treated with corticosteroid as one of the medications prescribed during the disease, any joint symptom specially in the hips should draw our attention to the joint infection, and with timely diagnosis and surgery, their hip joint can be saved.

摘要

目的

目前,COVID-19 感染后继发的股骨头缺血性坏死(AVN)和化脓性关节炎(SA)尚未见文献报道。由于在 COVID-19 病例中大量使用救命的皮质类固醇(CS),我们旨在警告这些患者髋关节感染的发生。

方法

我们报告了五例 COVID-19 感染患者在接受治疗后并发化脓性关节炎和 AVN 的病例。这些病例中使用的泼尼松龙平均剂量为 1695.2mg。我们病例中髋关节症状从 COVID-19 感染开始的发病时间分别为第 1 例 56 天,第 2 例 43 天,第 3 例 30 天,第 4 例 29 天,第 5 例 50 天,平均时间为 41.6 天。所有患者均根据关节软骨损伤程度采用直接前入路进行手术。

结果

所有患者的临床和实验室症状均明显改善。患者的平均视觉模拟疼痛评分从术前的 9.4(9-10)降至术后 1 周的 2.8(1-4)。

结论

对于任何有 COVID-19 感染史的患者,特别是那些曾用皮质类固醇作为治疗药物之一的患者,任何关节症状,特别是髋关节,都应引起我们对关节感染的关注,及时诊断和手术可以挽救他们的髋关节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c56/9169255/fa51288259c4/13018_2022_3192_Fig1_HTML.jpg

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