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一名患有新型冠状病毒肺炎相关心肌炎患者的心肺纤维化

Heart and Lung Fibrosis in a Patient with COVID-19-Related Myocarditis.

作者信息

Camastra Giovanni, Ciolina Federica, Arcari Luca, Cacciotti Luca, Pucci Mariateresa

机构信息

Cardiology Unit, General Hospital of Mother Giuseppina Vannini, Rome, Italy.

Radiology Unit, General Hospital of Mother Giuseppina Vannini, Rome, Italy.

出版信息

J Cardiovasc Echogr. 2022 Jan-Mar;32(1):52-53. doi: 10.4103/jcecho.jcecho_43_21. Epub 2022 Apr 20.

DOI:10.4103/jcecho.jcecho_43_21
PMID:35669133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9164915/
Abstract

A COVID-19 patient, in whom pneumonia lesions were first detected by chest computed tomography, was further evaluated by cardiac magnetic resonance (CMR) due to a suspected myocarditis. Beyond heart alterations, CMR revealed peculiar features of affected pulmonary areas in T1 mapping sequences and showed a particular distribution of late gadolinium enhancement in the same regions. The noninvasive assessment of the cellular, fluid, or fibrotic content of lung lesions may provide key information about the underlying pathophysiological pathways in the search of a tailored medical therapy and ventilatory support for COVID-19 patients.

摘要

一名新型冠状病毒肺炎(COVID-19)患者,最初通过胸部计算机断层扫描检测到肺部病变,因怀疑患有心肌炎,进一步接受了心脏磁共振成像(CMR)检查。除了心脏改变外,CMR在T1映射序列中显示了受影响肺部区域的特殊特征,并在同一区域显示了钆延迟强化的特定分布。对肺部病变的细胞、液体或纤维化成分进行无创评估,可能为寻找针对COVID-19患者的定制化药物治疗和通气支持提供有关潜在病理生理途径的关键信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9271/9164915/3902b0beb1ce/JCE-32-52-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9271/9164915/3902b0beb1ce/JCE-32-52-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9271/9164915/3902b0beb1ce/JCE-32-52-g001.jpg

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本文引用的文献

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Coronavirus disease 2019 in patients with cardiovascular disease: clinical features and implications on cardiac biomarkers assessment.2019 年冠状病毒病患者的心血管疾病:临床特征及其对心脏生物标志物评估的影响。
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Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19).COVID-19 患者近期康复后的心血管磁共振成像结果。
JAMA Cardiol. 2020 Nov 1;5(11):1265-1273. doi: 10.1001/jamacardio.2020.3557.
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Lung T1 mapping magnetic resonance imaging in the assessment of pulmonary disease in children with cystic fibrosis: a pilot study.
肺 T1 映射磁共振成像在囊性纤维化患儿肺部疾病评估中的应用:一项初步研究。
Pediatr Radiol. 2020 Jun;50(7):923-934. doi: 10.1007/s00247-020-04638-9. Epub 2020 Mar 11.
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Cardiac MR With Late Gadolinium Enhancement in Acute Myocarditis With Preserved Systolic Function: ITAMY Study.心脏磁共振钆延迟增强在急性心肌炎伴收缩功能保留中的应用:ITAMY 研究。
J Am Coll Cardiol. 2017 Oct 17;70(16):1977-1987. doi: 10.1016/j.jacc.2017.08.044.
6
Pulmonary fibrosis: tissue characterization using late-enhanced MRI compared with unenhanced anatomic high-resolution CT.肺纤维化:使用延迟强化磁共振成像与未增强的解剖学高分辨率计算机断层扫描对比进行组织特征分析
Diagn Interv Radiol. 2017 Mar-Apr;23(2):106-111. doi: 10.5152/dir.2016.15331.
7
Incidental extra-cardiac findings on clinical CMR.临床心脏磁共振检查中的偶然心脏外表现。
Eur Heart J Cardiovasc Imaging. 2013 Feb;14(2):158-66. doi: 10.1093/ehjci/jes133. Epub 2012 Jul 6.