基于质谱的视网膜蛋白质组学。
Mass spectrometry-based retina proteomics.
机构信息
Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas, USA.
出版信息
Mass Spectrom Rev. 2023 May;42(3):1032-1062. doi: 10.1002/mas.21786. Epub 2022 Jun 6.
Abstract
A subfield of neuroproteomics, retina proteomics has experienced a transformative growth since its inception due to methodological advances in enabling chemical, biochemical, and molecular biology techniques. This review focuses on mass spectrometry's contributions to facilitate mammalian and avian retina proteomics to catalog and quantify retinal protein expressions, determine their posttranslational modifications, as well as its applications to study the proteome of the retina in the context of biology, health and diseases, and therapy developments.
摘要
神经蛋白质组学的一个分支，视网膜蛋白质组学自成立以来，由于能够实现化学、生化和分子生物学技术的方法学进步，经历了变革性的增长。这篇综述重点介绍了质谱技术在促进哺乳动物和禽类视网膜蛋白质组学方面的贡献，以对视网膜蛋白质表达进行编目和定量，确定它们的翻译后修饰，以及将其应用于研究生物学、健康和疾病以及治疗发展背景下的视网膜蛋白质组。
相似文献
1
Mass spectrometry-based retina proteomics.基于质谱的视网膜蛋白质组学。
Mass Spectrom Rev. 2023 May;42(3):1032-1062. doi: 10.1002/mas.21786. Epub 2022 Jun 6.
2
Obtaining Complete Human Proteomes.获取完整的人类蛋白质组。
Annu Rev Genomics Hum Genet. 2022 Aug 31;23:99-121. doi: 10.1146/annurev-genom-112921-024948. Epub 2022 Apr 19.
3
Application of targeted mass spectrometry in bottom-up proteomics for systems biology research.靶向质谱在系统生物学研究中的蛋白质组学中的应用。
J Proteomics. 2018 Oct 30;189:75-90. doi: 10.1016/j.jprot.2018.02.008. Epub 2018 Feb 13.
4
Regulation of developmental processes: insights from mass spectrometry-based proteomics.发育过程的调控：基于质谱的蛋白质组学的见解
Wiley Interdiscip Rev Dev Biol. 2013 Sep-Oct;2(5):723-34. doi: 10.1002/wdev.102. Epub 2012 Dec 6.
5
Posttranslational modifications in systems biology.系统生物学中的翻译后修饰。
Adv Protein Chem Struct Biol. 2021;127:93-126. doi: 10.1016/bs.apcsb.2021.03.005. Epub 2021 Apr 17.
6
Mass Spectrometry-Based Chemical and Enzymatic Methods for Global Analysis of Protein Glycosylation.基于质谱的蛋白质糖基化全局分析的化学和酶学方法。
Acc Chem Res. 2018 Aug 21;51(8):1796-1806. doi: 10.1021/acs.accounts.8b00200. Epub 2018 Jul 16.
7
Overview and considerations in bottom-up proteomics.从头蛋白质组学的概述与考虑因素。
Analyst. 2023 Jan 31;148(3):475-486. doi: 10.1039/d2an01246d.
8
Emerging mass spectrometry-based proteomics methodologies for novel biomedical applications.新兴的基于质谱的蛋白质组学方法在新的生物医学中的应用。
Biochem Soc Trans. 2020 Oct 30;48(5):1953-1966. doi: 10.1042/BST20191091.
9
Identification, Quantification, and Site Localization of Protein Posttranslational Modifications via Mass Spectrometry-Based Proteomics.通过基于质谱的蛋白质组学对蛋白质翻译后修饰进行鉴定、定量及位点定位
Adv Exp Med Biol. 2016;919:345-382. doi: 10.1007/978-3-319-41448-5_17.
10
Proteomics approaches in the quest of kidney disease biomarkers.寻求肾脏疾病生物标志物的蛋白质组学方法。
Prilozi. 2011;32(2):33-51.
引用本文的文献
1
Genetically Engineered Liposwitch-Based Nanomaterials.基于基因工程脂开关的纳米材料。
Biomacromolecules. 2024 Dec 9;25(12):8058-8068. doi: 10.1021/acs.biomac.4c01388. Epub 2024 Nov 4.
2
The Prodrug DHED Delivers 17β-Estradiol into the Retina for Protection of Retinal Ganglion Cells and Preservation of Visual Function in an Animal Model of Glaucoma.前药 DHED 将 17β-雌二醇递送至视网膜，以保护青光眼动物模型中的视网膜神经节细胞和维持视觉功能。
Cells. 2024 Jun 29;13(13):1126. doi: 10.3390/cells13131126.
3
G protein-coupled receptors and traditional Chinese medicine: new thinks for the development of traditional Chinese medicine.G蛋白偶联受体与传统中药：传统中药发展的新思考
Chin Med. 2024 Jul 2;19(1):92. doi: 10.1186/s13020-024-00964-4.
4
Proteomics-Based Identification of Retinal Protein Networks Impacted by Elevated Intraocular Pressure in the Hypertonic Saline Injection Model of Experimental Glaucoma.基于蛋白质组学的方法鉴定高渗盐水注射诱导的实验性青光眼模型中眼压升高对视网膜蛋白网络的影响。
Int J Mol Sci. 2023 Aug 9;24(16):12592. doi: 10.3390/ijms241612592.
本文引用的文献
1
Proteomic Analysis of Retinal Tissue in an S100B Autoimmune Glaucoma Model.S100B自身免疫性青光眼模型中视网膜组织的蛋白质组学分析。
Biology (Basel). 2021 Dec 23;11(1):16. doi: 10.3390/biology11010016.
2
Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina.在米勒细胞中重新引入DJ-1可抑制DJ-1缺陷型视网膜的视网膜变性。
Antioxidants (Basel). 2021 Nov 23;10(12):1862. doi: 10.3390/antiox10121862.
3
Novel Regulators of Retina Neovascularization: A Proteomics Approach.新型视网膜新生血管调控因子：一种蛋白质组学方法。
J Proteome Res. 2022 Jan 7;21(1):101-117. doi: 10.1021/acs.jproteome.1c00547. Epub 2021 Dec 17.
4
Metabolic Imbalance Effect on Retinal Müller Glial Cells Reprogramming Capacity: Involvement of Histone Deacetylase SIRT6.代谢失衡对视网膜穆勒神经胶质细胞重编程能力的影响：组蛋白去乙酰化酶SIRT6的作用
Front Genet. 2021 Nov 4;12:769723. doi: 10.3389/fgene.2021.769723. eCollection 2021.
5
Proteomics analysis of N-methyl-d-aspartate-induced cell death in retinal and optic nerves.N-甲基-D-天冬氨酸诱导的视网膜和视神经细胞死亡的蛋白质组学分析。
J Proteomics. 2022 Feb 10;252:104427. doi: 10.1016/j.jprot.2021.104427. Epub 2021 Nov 13.
6
Targeted liquid chromatography-tandem mass spectrometry analysis of proteins: Basic principles, applications, and perspectives.靶向液相色谱-串联质谱分析蛋白质：基本原理、应用及展望。
Proteomics. 2021 Dec;21(23-24):e2100153. doi: 10.1002/pmic.202100153. Epub 2021 Oct 17.
7
Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males.基于蛋白质组学的视网膜靶点结合分析以及通过DHED前药实现17β-雌二醇的视网膜靶向递送用于男性眼部神经治疗
Pharmaceutics. 2021 Sep 2;13(9):1392. doi: 10.3390/pharmaceutics13091392.
8
Quantitative proteomic analysis after neuroprotective MyD88 inhibition in the retinal degeneration 10 mouse.神经保护 MyD88 抑制后视网膜变性 10 号小鼠的定量蛋白质组学分析。
J Cell Mol Med. 2021 Oct;25(20):9533-9542. doi: 10.1111/jcmm.16893. Epub 2021 Sep 25.
9
First identification of ITM2B interactome in the human retina.首次鉴定出人视网膜中的 ITM2B 相互作用组。
Sci Rep. 2021 Aug 26;11(1):17210. doi: 10.1038/s41598-021-96571-6.
10
Differential Retinal Protein Expression in Primary and Secondary Retinal Ganglion Cell Degeneration Identified by Integrated SWATH and Target-Based Proteomics.通过集成 SWATH 和靶向蛋白质组学鉴定原发性和继发性视网膜神经节细胞变性中的差异视网膜蛋白表达。
Int J Mol Sci. 2021 Aug 10;22(16):8592. doi: 10.3390/ijms22168592.
Zotero 插件