Dermatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte (CHULN), Lisbon, Portugal.
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257397.
Chondrosarcoma is the second-most common primary malignant bone tumor but chondrosarcoma of small bones of the hand is extremely rare, representing less than 2% of all cases, with exceedingly rare skin metastases. Cutaneous metastases of chondrosarcoma represent less than 3% of all cutaneous metastases. According to PubMed, there are only four previous case reports of cutaneous metastases originating from chondrosarcoma of small bones of the hand. We present an additional case of cutaneous metastases of phalangeal chondrosarcoma with a unique immunophenotype.
软骨肉瘤是第二常见的原发性骨恶性肿瘤,但手部小骨的软骨肉瘤极为罕见,不到所有病例的 2%,皮肤转移更为罕见。软骨肉瘤的皮肤转移占所有皮肤转移的比例不到 3%。根据 PubMed 的数据,仅有 4 例之前的病例报告涉及手部小骨的软骨肉瘤引起的皮肤转移。我们提出了一个具有独特免疫表型的指骨软骨肉瘤皮肤转移的附加病例。