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童年逆境和心理健康问题与严重攻击性行为个体双重危害的关联。

The association of childhood adversities and mental health problems with dual-harm in individuals with serious aggressive behaviors.

机构信息

Department of Psychiatry, The Second Xiangya Hospital, Central South University, National Clinical Research Center for Mental Disorders, National Technology Institute on Mental Disorders, Hunan Key Laboratory of Psychiatry and Mental Health, Renming Road 139, Changsha, 410011, Hunan Province, China.

Shenzhen Kangning Hospital, Shenzhen, China.

出版信息

BMC Psychiatry. 2022 Jun 7;22(1):385. doi: 10.1186/s12888-022-04027-6.

Abstract

BACKGROUND

The coexistence of self-harm and aggression, which is referred to as dual-harm, is commonly seen in forensic population. Self-harm and aggression have often been studied separately, previous studies on risk factors of aggression or self-harm mainly focused on childhood adversities, emotional regulation, impulsivity and psychopathology, given their importance in the two behaviors. However, the factors associated with dual-harm remain unclear. This study aimed to explore potential risk factors associated with co-occurring self-harm among individuals with serious aggressive behaviors.

METHODS

This multi-center, cross-sectional case-control study was conducted from May 2013 to January 2016 and involved seven qualified forensic institutes located in seven provinces in China. Participants were individuals with serious aggressive behaviors and were suspected to have mental disorders. Lifetime history of self-harm was obtained by a self-report questionnaire, and serious aggressive behaviors were assessed with the use of participants' forensic archive. Sociodemographic and clinical information were collected using a self-designed standardized data collection form, and childhood adversities was assessed using a clinician-rated scale designed by our research team. The Psychopathy Checklist-Revised (PCL-R) was used to assess psychopathic traits and the Brief Psychiatric Rating Scale (BPRS) was used to assess psychiatric symptoms of the participants. Univariate and multivariate logistic regression analyses were performed to analyze the relevant factors for dual-harm.

RESULTS

A total of 423 individuals with serious aggressive behaviors were enrolled in the current study. Of them, 74 (17.5%) with self-harm history assigned into the dual-harm group (D-H) and 349 (82.5%) without self-harm history assigned into the aggression-only group (A-O). According to the binary logistic regression analysis, current diagnosis of mood disorder (OR = 3.2, 95%CI: 1.2-8.5), child abuse (OR = 2.8, 95%CI: 1.3-6.2), parental death (OR = 3.0, 95%CI: 1.2-7.5), and the score of the affective subscale in BPRS (OR = 1.7, 95%CI: 1.3-2.4) were significantly associated with dual-harm.

CONCLUSIONS

Our study suggested the necessity of integrated evaluation of self-harm among individuals with serious aggressive behaviors. Childhood adversities and psychiatric symptoms in this population require special attention.

摘要

背景

自伤和攻击行为同时存在,被称为双重伤害,在法医人群中很常见。自伤和攻击行为通常是分开研究的,以前关于攻击或自伤风险因素的研究主要集中在童年逆境、情绪调节、冲动和精神病理学上,因为它们在这两种行为中都很重要。然而,与双重伤害相关的因素仍不清楚。本研究旨在探讨与严重攻击行为个体中同时发生的自伤相关的潜在风险因素。

方法

这是一项多中心、横断面病例对照研究,于 2013 年 5 月至 2016 年 1 月进行,涉及中国七个省的七家合格法医机构。参与者为严重攻击行为者,并被怀疑患有精神障碍。通过自我报告问卷获得终生自伤史,使用参与者的法医档案评估严重攻击行为。使用我们研究团队设计的临床医生评定量表评估童年逆境,使用自我设计的标准化数据收集表收集人口统计学和临床信息。使用修订后的心理检查表(PCL-R)评估精神变态特征,使用简明精神病评定量表(BPRS)评估参与者的精神病症状。采用单因素和多因素逻辑回归分析双重伤害的相关因素。

结果

本研究共纳入 423 名严重攻击行为者。其中,74 名(17.5%)有自伤史,归入双重伤害组(D-H),349 名(82.5%)无自伤史,归入仅攻击组(A-O)。根据二元逻辑回归分析,当前诊断为心境障碍(OR=3.2,95%CI:1.2-8.5)、儿童虐待(OR=2.8,95%CI:1.3-6.2)、父母死亡(OR=3.0,95%CI:1.2-7.5)和 BPRS 情感分量表得分(OR=1.7,95%CI:1.3-2.4)与双重伤害显著相关。

结论

本研究表明,有必要对严重攻击行为个体的自伤进行综合评估。该人群中的童年逆境和精神症状需要特别关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/548a/9175457/2e56ebfb20ef/12888_2022_4027_Fig1_HTML.jpg

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