Adomonis V M, Bredikis Iu Iu, Bukauskas F F, Lukoshiavichius K K, Mutskus K S
Biull Eksp Biol Med. 1987 Apr;103(4):387-90.
The heart rate and intraatrial latencies between epicardial electrograms from three sites of the right atrium have been studied during vagal stimulation in open-chest dogs. It has been shown that alterations of latencies started at a certain cardiac cycle length irrespective of pacing frequency. A transitional process of changes from a steady latency value in the control to another steady value during vagal stimulation has been observed. The transitional process has been simulated in experimental procedure in which two sites of the right atrium were paced at close and constant frequencies. To interpret the results obtained one-dimensional model of the sinus node has been constructed. According to the model, pacemaker shift within the sinus node results from a competition between two foci of automaticity with close intrinsic frequencies.
在开胸犬迷走神经刺激期间,研究了右心房三个部位的心外膜电图之间的心率和心房内潜伏期。结果表明,潜伏期的改变始于特定的心动周期长度,与起搏频率无关。观察到在迷走神经刺激期间,从对照中的稳定潜伏期值到另一个稳定值的转变过程。在实验过程中模拟了这种转变过程,其中右心房的两个部位以接近且恒定的频率起搏。为了解释所获得的结果,构建了窦房结的一维模型。根据该模型,窦房结内的起搏点移位是由两个固有频率相近的自律中心之间的竞争引起的。