Vardosanidze E Sh, Pirtskhalashvili D S, Darakhvelidze M A, Kikvadze Ts G
Biull Eksp Biol Med. 1987 Apr;103(4):460-2.
It has been demonstrated that tumours do not appear after subcutaneous transplantation of small amounts (10(2), 2 X 10(2] of AD-12 sarcoma cells to intact hamsters, whereas tumours do appear in 53-72% of hamsters inoculated with starch suspension prior to transplantation of the same amounts of tumour cells (tumour growth stimulation phenomenon). The results show that tumour growth stimulation in hamsters pre-inoculated with starch suspension is connected with distraction of macrophages from the region of tumour cell localization to the abdominal area.
已经证明,将少量(10²、2×10²)AD - 12肉瘤细胞皮下移植到完整的仓鼠体内后不会出现肿瘤,而在移植相同数量肿瘤细胞之前接种淀粉悬浮液的仓鼠中,有53 - 72%会出现肿瘤(肿瘤生长刺激现象)。结果表明,预先接种淀粉悬浮液的仓鼠中肿瘤生长刺激与巨噬细胞从肿瘤细胞定位区域转移到腹部区域有关。