Lisatova N G, Boĭkov A K, Boĭkova S P
Biull Eksp Biol Med. 1987 Apr;103(4):495-8.
Histological and electron microscopic studies of embryos from pulmonectomized female rats have revealed retarded differentiation of respiratory rudiment epithelium manifested in delayed appearance of osmiophylic laminar corpuscles and decreased number of type II pneumocytes in respiratory rudiment lining. Osmiophylic laminar corpuscles in them were less differentiated, as compared to the control. In addition, embryonic lungs in pulmonectomized rats were characterized by excessive mesenchyma development and respective decrease in respiratory rudiment area. It is concluded that embryonic lungs developed during pulmonary tissue deficit in the mother are functionally less mature.
对肺切除雌性大鼠胚胎进行的组织学和电子显微镜研究显示，呼吸原基上皮的分化延迟，表现为嗜锇性板层小体出现延迟以及呼吸原基衬里中II型肺细胞数量减少。与对照组相比，它们的嗜锇性板层小体分化程度较低。此外，肺切除大鼠的胚胎肺特征为间充质过度发育以及呼吸原基面积相应减小。得出的结论是，在母体肺组织缺失期间发育的胚胎肺在功能上不太成熟。
